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Table 2 Association between probable risk factors and time to complete retinal vascularization in retinopathy of prematurity patients

From: Progression of retinal vascularization after intravitreal anti-vascular-endothelial growth factor therapy in retinopathy of prematurity

Parameter

Level

Total (%)

Full vessel (%)

Adjusted model

Final model

 

AHR

95% CI

p

AHR

95% CI

p

Lower

Upper

Lower

Upper

GA 30 weeks

Under 30

739 (86%)

514 (72.9%)

0.734

0.574

0.939

0.014

0.718

0.566

0.912

0.007

GAC30

 

31 + 

120 (%14)

96 (82.2%)

Ref

        

BW 1000 g

Under 1000

400 (46%)

266 (69.5%)

0.866

0.727

1.031

0.106

0.853

0.718

1.012

0.069

BW1000

 

1000 + 

459 (53%)

344 (78.4%)

Ref

        

Gender

Male

252 (57%)

193 (76.7%)

0.967

0.819

1.141

0.690

     
 

Female

189 (43%)

188 (71.3%)

Ref

        

NVI

Yes

54 (6%)

33 (68.8%)

0.742

0.515

1.070

0.110

0.714

0.501

1.019

0.063

NVI

 

No

811 (94%)

584 (74.8%)

Ref

        

Twin

Yes

210 (24%)

148 (73.0%)

1.204

0.990

1.464

0.063

1.227

1.016

1.482

0.034

Twin

 

No

655 (76%)

468 (74.9%)

Ref

        

O2 therapy

Yes

764 (88%)

537 (73.7%)

0.944

0.737

1.210

0.650

     
 

No

99 (11%)

79 (79.8%)

Ref

        

Intubation

Yes

348 (40%)

236 (70.9%)

0.809

0.674

0.971

0.023

0.793

0.669

0.939

0.007

Intubation

 

No

515 (60%)

380 (76.8%)

Ref

        

Transfusion

Yes

491 (57%)

351 (74.7%)

0.906

0.751

1.092

0.300

     
 

No

372 (43%)

264 (74.0%)

Ref

        

IVH

Yes

62 (7%)

43 (72.9%)

1.134

0.827

1.556

0.434

     
 

No

801 (93%)

572 (74.5%)

Ref

        

Sepsis

Yes

340 (39%)

233 (71.3%)

1.001

0.829

1.207

0.996

     
 

No

523 (60%)

382 (76.4%)

Ref

        

Phototherapy

Yes

572 (66%)

403 (74.5%)

0.797

0.658

0.966

0.020

0.783

0.659

0.929

0.005

Photo therapy

 

No

291 (33%)

212 (74.2%)

Ref

        

Anemia

Yes

76 (9%)

35 (48.6%)

1.493

0.997

2.237

0.052

1.428

1.003

2.034

0.048

Anemia

 

No

787 (91%)

579 (76.9%)

Ref

        

ARDS

Yes

457 (53%)

360 (82.6%)

1.005

0.823

1.227

0.961

     
 

No

406 (47%)

255 (65.3%)

Ref

        

Pretreatment zone

1

187 (21%)

112 (60%)

0.899

0.723

1.117

0.335

     
 

2

678 (78%)

506 (74%)

Ref

        
  1. AHR adjusted hazard ratio, ARDS acute respiratory distress syndrome, BW birth weight, GA gestational age, IVH intra-ventricular hemorrhage, NVI neovascularization of iris