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Table 7 Correlation of plasma level of conventional lipid components, TL and FFA with vitreous level of LPOs and ALE and VEGF in DR (MNPDR + HRPDR) subjects

From: Do different lipid components accelerate the pathogenesis and severity of Diabetic Retinopathy?

Parameters

MDA(µmol/L)

HNE(pg/ml)

HLY (nmol/L)

VEGF (pg/L)

TCH (mg/dl)

r = 0.542, p = 0.010

r = 0.451, p = 0.026

r = 0.431, p = 0.024

r = 0.524, p = 0.014

LDL-C (mg/dl)

r = 0.512, p = 0.016

r = 0.592, p = 0.002

r = 0.552, p = 0.012

r = 0.439, p = 0.028

HDL-C (mg/dl)

r = 0.136, p = 0.415

r = 0.174, p = 0.395

r = 0.161, p = 0.423

r = 0.191, p = 0.381

TG (mg/dl)

r = 0.693, p < 0.0001

r = 0.586, p = 0.012

r = 0.541, p = 0.023

r = 0.536, p = 0.011

TL (mg/dl)

r = 0.752, p < 0.0001

r = 0.481, p = 0.018

r = 0.591, p = 0.002

r = 0.616, p = 0.001

FFA (mmol/L)

r = 0.610, p = 0.001

r = 0.475, p = 0.024

r = 0.691, p < 0.0001

r = 0.453, p = 0.026

  1. The DNR, MNPDR and HRPDR groups are combined together and termed as Type 2 Diabetes Mellitus (T2DM) group. Pearson or Spearman's rank correlation coefficient (r) was used and a value of p < 0.05 was considered as statistically significant
  2. TCH, total cholesterol; LDL-C, low density lipoprotein cholesterol, HDL-C, high density lipoprotein cholesterol; TG, triglycerides; TL, total lipid; FFA, free fatty acid; HNE, 4-Hydroxynonenal; MDA, malondialdehyde; HLY, hexanoyl-lysine; VEGF, vascular endothelial growth factor