Group | Hole Size (MLD) (µm) | Hole-edge configuration | edematous edges | MHI (Height/BLD) | VMT | ERM |
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VMT | | | Focal/ Diffuse | |
Small | < 250 | Cuff or flat | Yes/no | | Yes/no | Yes/no |
Medium | > 250 to ≤ 400 | Cuff or flat | Yes/no | | Yes/no | Yes/no |
Large | > 400 to ≤ 550 | Cuff or flat | Yes/no | | Yes/no | Yes/no |
X-Large | > 550 to ≤ 800 | Cuff or flat | Yes/no | | Yes/no | Yes/no |
XX-Large | > 800 to ≤ 1000 | Cuff or flat | Yes/no | | Yes/no | Yes/no |
Giant | > 1000 | Cuff or flat | Yes/no | | Yes/no | Yes/no |
- MLD minimum linear diameter, MHI macular hole index, BLD base linear diameter, cuff = separation of photoreceptors at hole edges from the retinal pigment epithelium (RPE) with difference between MLD and BLD ≥ 200 µm; flat no separation of photoreceptors from RPE or minimal separation with difference between MLD and BLD < 200 µm; edematous edges presence of multiple cystoid cavities at hole edges; VMT vitreomacular traction; focal ≤ 1500 µm; diffuse > 1500 µm; ERM epiretinal membrane