Predictive value of retinal oximetry, optical coherence tomography angiography and microperimetry in patients with treatment-naïve branch retinal vein occlusion

Table 2 Logistic regression results of novel markers, in predicting 12 month outcomes in patients with BRVO treated with aflibercept

		Need of additional aflibercept after loading		Macular edema at month 12		Improvement of 10 or more ETDRS letters from baseline
	Predictor increment	Adjusted odds ratio (95% CI)	Adjusted p-value	Adjusted odds ratio (95% CI)	Adjusted p-value	Adjusted odds ratio (95% CI)	Adjusted p-value
Retinal oximetry (n = 33)
Arteriolar saturation (%)	1%	0.80 (0.64;1.00)	0.054	0.94 (0.85;1.03)	0.175	1.05 (0.96;1.16)	0.265
Venular saturation (%)	1%	0.96 (0.89;1.04)	0.379	0.97 (0.91;1.03)	0.282	1.00 (0.94;1.06)	0.938
OCT-A, SCP
Area of FAZ (mm²) (n = 20)	0.01 mm²	0.79 (0.55;1.12)	0.187	0.88 (0.76;1.03)	0.105	1.08 (0.98;1.19)	0.125
Area of non-perfusion (mm²) (n = 27)	0.01 mm²	0.62 (0.20;1.92)	0.409	0.86 (0.34;2.15)	0.748	0.76 (0.30;1.90)	0.554
Vessel density (%) (n = 27)	1%	1.08 (0.89;1.30)	0.428	1.01 (0.87;1.18)	0.865	1.06 (0.91;1.23)	0.481
Fractal dimension (n = 27)	0.01	1.02 (0.32;3.22)	0.973	0.89 (0.37;2.13)	0.799	2.02 (0.82;4.98)	0.124
Microperimetry (n = 39)
Mean retinal sensitivity (dB)	1 dB	1.00 (0.70;1.44)	0.982	1.08 (0.79;1.46)	0.631	0.96 (0.68;1.35)	0.800

Presented as odds ratio with 95% confidence interval and p-value of logistic regression model adjusted for age, sex, baseline central retinal thickness and baseline best corrected visual acuity of the variable in question. Predictor increment are the increment of the given variable for which the odds ratio apply.
BRVO = branch retinal vein occlusion, SCP = superficial capillary plexus, FAZ = foveal avascular zone, dB = decibel, ETDRS = early treatment diabetic retinopathy study.

ISSN: 2056-9920