Table 1 Baseline characteristics, objective and subjective assessments prior to injections
Variable | Description | All | 3ML | 10ML (n = 45) | 15ML (n = 46) | p-value |
|---|---|---|---|---|---|---|
(n = 142) | (n = 51) | |||||
RACE: | African American | 9 (6.3%) | 1 (2.0%) | 2 (4.4%) | 6 (13.0%) | 0.0893 |
Mixed | 3 (2.1%) | 1 (2.2%) | 2 (4.3%) | |||
Native American | 10 (7.0%) | 2 (3.9%) | 2 (4.4%) | 6 (13.0%) | ||
Native Hawaiian/ | 1 (0.7%) | 1 (2.2%) | ||||
Pacific Islander | ||||||
Other | 5 (3.5%) | 2 (3.9%) | 2 (4.4%) | 1 (2.2%) | ||
White/Caucasian | 114 (80.3%) | 46 (90.2%) | 38 (84.4%) | 30 (65.2%) | ||
GENDER: | Female | 73 (51.4%) | 22 (43.1%) | 26 (57.8%) | 25 (54.3%) | 0.3298 |
Male | 69 (48.6%) | 29 (56.9%) | 19 (42.2%) | 21 (45.7%) | ||
STUDY EYE: | OD | 83 (58.5%) | 30 (58.8%) | 26 (57.8%) | 27 (58.7%) | 1 |
OS | 59 (41.5%) | 21 (41.2%) | 19 (42.2%) | 19 (41.3%) | ||
FLUORESCEIN STAINING: | 0 | 33 (23.2%) | 13 (25.5%) | 8 (17.8%) | 12 (26.1%) | 0.4235 |
I | 45 (31.7%) | 15 (29.4%) | 15 (33.3%) | 15 (32.6%) | ||
II | 30 (21.1%) | 10 (19.6%) | 14 (31.1%) | 6 (13.0%) | ||
III | 18 (12.7%) | 7 (13.7%) | 6 (13.3%) | 5 (10.9%) | ||
IV | 16 (11.3%) | 6 (11.8%) | 2 (4.4%) | 8 (17.4%) | ||
TBUT | 0–5 s | 68 (47.9%) | 25 (49.0%) | 22 (48.9%) | 21 (45.7%) | 0.4032 |
6–10 s | 47 (33.1%) | 18 (35.3%) | 17 (37.8%) | 12 (26.1%) | ||
> 10 s | 27 (19.0%) | 8 (15.7%) | 6 (13.3%) | 13 (28.3%) | ||
SCHIRMER TEST | < 5 mm | 15 (10.6%) | 5 (9.8%) | 6 (13.3%) | 4 (8.7%) | 0.7883 |
>= 5 mm | 127 (89.4%) | 46 (90.2%) | 39 (86.7%) | 42 (91.3%) | ||
OSDI | mean and std | 18.1 (17.9) | 20.3 (20.0) | 17.0 (15.3) | 16.7 (18.0) | 0.5546 |
median and IQR | 11.4 (4.5, 27.5) | 15.9 (2.8, 31.8) | 10.4 (5.0, 27.3) | 9.1 (4.5, 22.7) | ||
min and max | (0.0, 94.4) | (0.0, 94.4) | (0.0, 52.5) | (0.0, 72.7) | ||
#(%) missing | 1 (0.7%) | 1 (2.2%) | ||||
SPEED II | mean and std | 4.1 (4.5) | 3.4 (3.9) | 4.6 (5.0) | 4.5 (4.6) | 0.318 |
median and IQR | 3.0 (0.0, 6.0) | 2.0 (0.0, 6.0) | 3.0 (1.0, 7.0) | 4.0 (0.0, 7.0) | ||
min and max | (0.0, 22.0) | (0.0, 17.0) | (0.0, 22.0) | (0.0, 20.0) | ||
#(%) missing | 1 (0.7%) | 1 (2.2%) |