Figure 10

OCTA and FA of Microaneurysms in NPDR. The right eye (A) and left eye (B) of a 45 year old Caucasian man with non-proliferative diabetic retinopathy using the swept source optical coherence tomography angiography (OCTA) prototype (Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachussetts Insitute of Technology, Cambridge, MA). (A1) Fluorescein angiography (FA) cropped to approximately 6 x 6 mm. Aneurysms are circled in yellow. (A2) Full-thickness (internal limiting membrane to Bruch’s membrane) 6 x 6 mm OCT angiogram. FAZ appears enlarged. Aneurysms that are seen on FA in A1 that are also seen on OCTA are circled in yellow. Aneurysms on FA that are seen as areas of capillary non-perfusion on OCTA are circled in blue. Areas where aneurysms are seen on FA, but show normal vasculature on OCTA are circled in red. (B1) FA cropped to approximately 3 x 3 mm. Aneurysms are circled in yellow. (B2) Full-thickness 3 x 3 mm OCT angiogram, which provides improved detail over 6 x 6 mm OCT angiograms, demonstrates higher sensitivity in detecting micro vascular abnormalities. FAZ appears enlarged. Aneurysms that are seen on FA in B1 that are also seen on OCTA are circled in yellow. Aneurysms on FA that are seen as areas of capillary non-perfusion on OCTA are circled in blue.