Figure 11

OCTA of NPDR. The right eye (A) and left eye (B) of a 58 year old Caucasian man with non-proliferative diabetic retinopathy and diabetic macular edema (DME) using the Angiovue optical coherence tomography angiography (OCTA) software of the RTVue XR Avanti (Optovue, Inc., Fremont, CA). (A1) Full-thickness (internal limiting membrane to Bruch’s membrane) 6 x 6 mm OCT angiogram shows microvascular abnormalities such as areas of capillary non-perfusion (yellow arrows), capillary loops, and microaneurysms. (A2) En-face structural OCT with a red line corresponding to the highly-sampled OCT b-scan in A3. (A3) 12 mm highly sampled OCT b-scan through the fovea demonstrating DME and hard exudates. (B1) Full-thickness 3 x 3 mm OCT angiogram, which provides improved detail over 6 x 6 mm OCT angiograms, shows microvascular abnormalities such as areas of capillary non-perfusion (yellow arrows), capillary loops, and microaneurysms. (B2) En-face structural OCT with a red line corresponding to the highly-sampled OCT b-scan in B3. (B3) 12 mm highly sampled OCT b-scan through the fovea demonstrating DME and hard exudates.