Figure 12

OCTA of Neovascularization in PDR. (A) The right eye of a 74 year old African woman with neovascularization of the disc (NVD) due to proliferative diabetic retinopathy (PDR) using the Angiovue optical coherence tomography angiography (OCTA) software of the RTVue XR Avanti (Optovue, Inc., Fremont, CA). (A1) Color fundus photo demonstrating fine neovascular vessels over the optic disc. (A2) Full-thickness (internal limiting membrane to Bruch’s membrane) 3 x 3 mm OCT angiogram at the optic disc. Wispy NVD is difficult to appreciate. (A3) 3 x 3 mm OCT angiogram at the optic disc segmented with the inner boundary in the vitreous above the NVD and the outer boundary slightly below the internal limiting membrane (ILM). The NVD is clearly appreciable. (A4) En-face structural OCT showing abnormal tissue at the optic disc. (A5) Highly-sampled OCT b-scan of the optic disc where abnormal tissue is observed extending above the ILM into the vitreous cavity. (B) The right eye of a 46 year old African woman with neovascularization elsewhere (NVE) due to proliferative diabetic retinopathy (PDR) using the Angiovue optical coherence tomography angiography (OCTA) software of the RTVue XR Avanti (Optovue, Inc., Fremont, CA). (B1) 3 x 3 mm OCT angiogram with the inner boundary in the vitreous and the outer boundary at Bruch’s membrane. Abnormal vessels are seen in an area of capillary non-perfusion. Image quality is limited by artifact from movement (horizontal and vertical lines). (B2) Corresponding OCT b-scan showing abnormal tissue above the ILM extending into the vitreous cavity.