Figure 7

OCTA and FA/ICGA of CNV in Neovascular AMD. The left eye of a 67 year old Caucasian man with choroidal neovascularization (CNV) due to neovascular age-related macular degeneration using the Angiovue optical coherence tomography angiography (OCTA) software of the RTVue XR Avanti (Optovue, Inc., Fremont, CA). (A) 6 x 6 mm OCT angiogram segmented so both the choriocapillaris and the outer retina are shown. A circular net of abnormal vessels are shown surrounded by relatively homogenous choriocapillaris. The abnormal vessels exist both below and above Bruch’s membrane (in the outer retina). (B) En-face structural OCT with a red line corresponding to the highly-sampled OCT b-scan in C. (C) 12 mm highly sampled OCT b-scan through the fovea demonstrates a large retinal pigment epithelial detachment, subretinal fluid, disruption of Bruch’s membrane, and hyper-reflective material characteristic of CNV. (D) Indocyanine green angiography early, intermediate, and late frames show increasing hyper-fluorescence and pooling of dye in the CNV. (E) Fluorescein angiography intermediate and late frames show increasing hyper-fluorescence and pooling of the CNV.