Fig. 1

Multimodal imaging findings of angioid streaks at baseline visit. Color (a) and red-free (RF) photographs (b) of the right eye show angioid streaks at the peripapillary region radiating into the fovea. Late-phase fluorescein angiogram (c; FA) shows variable staining of the angioid streaks with no leakage. Fundus autofluorescence (d; FAF) imaging shows areas of hypoautofluorescence in the peripapillary area that are greater in size than the corresponding AS seen on color photography. AS correlate to breaks within the Bruch’s membrane (yellow arrow) as seen on spectral domain optical coherence tomography (e; SD-OCT). The yellow line indicates the location of the SD-OCT scan.