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Table 2 A summary of the major published series of PPV treatments for ODP-M

From: Optic disc pit maculopathy: when and how to treat? A review of the pathogenesis and treatment options

References

No. of cases

PPV gauge

Surgical technique

Main results

Complications

Taiel-Sartral et al. [64]

10

20

PPV+laser+gas

VA improved in 90%

Mean VA improvement of 6.7 lines

Complete resolution in 70%

1 recurrence (10%)

None

García-Arumí et al. [67]

11

20

PPV+PVD+laser +gas

82% gained ≥2 lines of VA

Mean final VA 20/32

Complete resolution in all cases

2 recurrences (18%)

None

Hirakata et al. [37]

11

20

PPV+PVD+gas

VA improved in 64%

Complete resolution 91%

Showed that laser may not be required for surgical success

1 patient developed a dense inferotemporal scotoma

1 patient developed an area of retinal atrophy

1 patient had an intraoperative retinal break, treated with laser

Ghosh et al. [71]

7

20

PPV+PVD+laser +gas

4 (57%) gained ≥2 lines of VA

4 (57%) required second procedure

Silicone oil was successful in a refractive case

1 patient developed postoperative glaucoma and cataract

Rizzo et al. [80]

10

23/25

PPV+PVD+ILMP +laser+gas

70% gained ≥2 lines of VA

Complete resolution in 50%

First report with small gauge PPV

1 complication—macular hole

Hirakata et al. [38]

8

20/25

PPV+PVD (no gas)

VA improved in 7 (88%) eyes Complete resolution in 88%

Suggested that gas tamponade may be less important than induction of PVD

None

Shukla et al. [81]

7

23

PPV+PVD+ILMP +laser+gas

6 (86%) eyes gained ≥2 lines of VA

Final VA ≥20/30 in 5 (71%) eyes

4 eyes had full thickness macular holes at 1 month, but it closed in 3 of them

2 patients had transient elevated intraocular pressure

1 patient developed cataract

Avci et al. [83]

13

23

PPV+PVD+laser +gas

11 (85%) eyes gained ≥2 lines of VA

Final VA ≥20/40 in 6 (46%) eyes

Complete resolution in 92%

Suggests ILMP may not be required for surgical success

2 patients developed cataracts

Gregory-Roberts et al. [39]

9

N/A

PPV+PVD+glial tissue removal+laser +gas

Complete resolution in 8 (89%) eyes

Higher rate of complete resolution when glial tissue was removed over the pit

1 patient developed cataract

Ooto et al. [90]

18

25

PPV+intraretinal fenestration

Complete resolution in 94%

VA improved in all eyes

11 (61%) eyes gained ≥3 lines of VA

Final VA ≥20/30 in 10 (56%) eyes

None

  1. Presented are the only studies that included more than five patients with ODP-M that were treated using a uniform PPV technique. PPV pars plana vitrectomy, ODP-M optic disc pit maculopathy, PVD induction of posterior vitreous detachment, laser laser photocoagulation temporal to disc, gas gas tamponade, ILMP internal limiting membrane peeling and VA visual acuity.