Fig. 8

Clinical course of Patient 4. Serial spectral-domain optical coherence tomography (SD-OCT) images taken approximately every 2 years demonstrate gradual progression of central geographic atrophy and the development of outer retinal tubulations in the left eye (right panel). In the right eye (left panel), there is broad type 1 NV. Color fundus and fundus autofluorescence images acquired at the final visit demonstrate a greater area of atrophy (yellow lines) in the left eye relative to the right. SD-OCT image of the final visit also reveals persistent type 1 NV in the right eye with intraretinal edema