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Table 1 Mean scotopic and photopic ERG a- and b-wave amplitudes in different groups at different time points

From: Safe dose of intravitreal imatinib and its effect on laser-induced choroidal neovascularization: a rat-model experiment

  Time   Group F Group E Group D Group C Group B Group A P value  
Photopic ERG a-wave amplitude (µv) Base Value 22.85 ± 28.57 19.48 ± 20.36 12.47 ± 5.91 12.45 ± 16.98 13.13 ± 9.19 12.86 ± 13.77 0.841  
Week 1 Value 14.83 ± 11.72 11.17 ± 5.57 8.9 ± 6.59 10.84 ± 8.02 12.22 ± 7.73 10.38 ± 9.21 0.540*  
Within P 0.684 0.528 0.541 1.000 1.000 1.000   
Week 4 Value 9.92 ± 4.46 8.25 ± 6.13 6.68 ± 5.73 10.46 ± 5.62 12.66 ± 10.67 8.07 ± 7.17 0.285*  
Within P 0.679 0.293 0.142 1.000 1.000 1.000   
Photopic ERG b-wave amplitude (µv) Base Value 39.55 ± 16.06 49.47 ± 16.29 36.25 ± 18.16 34.54 ± 30.04 47.82 ± 32.77 31.13 ± 15.47 0.721  
Week 1 Value 28.83 ± 10.94 36.38 ± 17.26 28.88 ± 13.28 29.87 ± 17.7 44.72 ± 32.98 30.8 ± 17.31 0.277*  
Within P 0.165 0.523 0.222 1.000 1.000 1.000   
Week 4 Value 35.48 ± 17.57 38.45 ± 31.76 26.73 ± 10.26 29.45 ± 12.36 25.18 ± 22.11 30.29 ± 25.66 0.853*  
Within P 0.934 1.000 0.205 1.000 0.276 1.000   
Scotopic ERG a-wave amplitude (µv) Base Value 77.19 ± 36.94 45.69 ± 24.72 34.43 ± 18.89 47.86 ± 36.06 51.19 ± 17.11 54.33 ± 17.06 0.079  
Week 1 Value 68.69 ± 38.25 43.15 ± 42.86 31.21 ± 16.94 44.83 ± 24.19 43.18 ± 27.21 24.26 ± 14.82 0.024* F Vs A
Within P 1.000 1.000 1.000 1.000 0.772 0.000   
Week 4 Value 57.89 ± 11.08 54.52 ± 67.42 19.74 ± 15.09 30.86 ± 30.34 32.14 ± 24.89 25.64 ± 13.44 0.135*  
Within P 0.522 1.000 0.172 0.590 0.141 0.000   
Scotopic ERG b-wave amplitude (µv) Base Value 153.03 ± 83.46 186.2 ± 71.72 145.13 ± 45.81 126.6 ± 43.54 155.41 ± 52.43 154.32 ± 58.28 0.163  
Week 1 Value 129.98 ± 48.91 169.2 ± 53.28 125.86 ± 87.19 73.5 ± 20.77 98.01 ± 39.99 70.66 ± 44.32 0.003* F Vs C & A
Within P   1.000 1.000 0.928 0.026 0.061 0.000   
Week 4 Value 102.13 ± 122.37 142.84 ± 68.11 88.57 ± 61.39 55.95 ± 29.69 90.23 ± 72.82 58.85 ± 41.12 0.195  
Within P 0.626 0.623 0.046 0.001 0.031 0.000   
  1. Based on Mixed analysis, adjusted for the multiple comparison by Bonferroni method
  2. Based on Mann–Whitney test
  3. * Adjusted for the baseline, based on analysis of covariance