Table 2 Optical coherence tomography measurements and visual acuity over the course of medication changes

Central macular thickness (CMT), μm

 OCT 1

317 (259.5–362.5)

 OCT 2

285 (228–337)

0.034^a

 OCT 3

296 (231.5–409)

0.080^b

 OCT 4

283 (229.5–374.5)

0.016^c

Total fluid volume^d, mm³

 OCT 1

2.56 (1.05–4.47)

 OCT 2

2.44 (1.03–4.54)

0.080^a

 OCT 3

3.18 (0.96–4.39)

0.019^b

 OCT 4

2.11 (0.82–3.57)

0.016^c

Subretinal fluid (SRF), mm³

 OCT 1

0.16 (0.01–0.88)

 OCT 2

0.19 (0.006–0.59)

0.018^a

 OCT 3

0.34 (0.04–1.42)

0.057^b

 OCT 4

0.11 (0–0.36)

0.003^c

Intraretinal fluid (IRF), mm³

 OCT 1

0.007 (0–0.44)

 OCT 2

0.002 (0–0.11)

0.102^a

 OCT 3

0.12 (0–0.78)

0.019^b

 OCT 4

0.0005 (0–0.44)

0.336^c

Pigment epithelial detachment (PED), mm³

 OCT 1

2.00 (0.64–3.27)

 OCT 2

1.64 (0.71–3.40)

0.307^a

 OCT 3

1.95 (0.65–2.79)

0.238^b

 OCT 4

1.76 (0.53–2.55)

0.179^c

Visual acuity (VA), logMAR^e

 OCT 1

0.30 (0.18–0.48)

 OCT 2

0.30 (0.18–0.44)

0.175^a

 OCT 3

0.30 (0.14–0.57)

0.292^b

 OCT 4

0.30 (0.18–0.60)

0.104^c