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Table 1 Comparison of laboratory tests currently available for prognosis of posterior uveal melanomas

From: Clinical application of genetic testing for posterior uveal melanoma

  Karyotype FISH CGH GEP MLPA
Type of analyses Chromosomes DNA DNA RNA or DNA DNA
Monosomy 3 detection Yes Yes Yes No Yes
Tissue used FFPE FFPE FFPE FFPE or fresh FFPE or fresh
Reported tumor heterogeneity NR NR NR 11.3 % 75 %
  1. FISH fluorescence in situ hybridization; CGH comparative genomic hybridization; MLPA multiplex ligation-dependent probe amplification; GEP gene expression profiling; FFPE formalin fixed paraffin embedded; NR not reported