Clinical application of genetic testing for posterior uveal melanoma

Table 1 Comparison of laboratory tests currently available for prognosis of posterior uveal melanomas

	Karyotype	FISH	CGH	GEP	MLPA
Type of analyses	Chromosomes	DNA	DNA	RNA or DNA	DNA
Monosomy 3 detection	Yes	Yes	Yes	No	Yes
Tissue used	FFPE	FFPE	FFPE	FFPE or fresh	FFPE or fresh
Reported tumor heterogeneity	NR	NR	NR	11.3 %	75 %

FISH fluorescence in situ hybridization; CGH comparative genomic hybridization; MLPA multiplex ligation-dependent probe amplification; GEP gene expression profiling; FFPE formalin fixed paraffin embedded; NR not reported

ISSN: 2056-9920