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Table 3 Predictors of the change of MPOD (ΔMPOD) after a median follow-up of 3.96 years; the results are presented as regression coefficients (β) from multivariate regression models

From: Changes of macular pigment optical density in elderly eyes: a longitudinal analysis from the MARS study

  Change of MPOD (ΔMPOD)*
At 0.25° At 0.5° At 1.0° At 2.0°
Predictors β p value β p value β p value β p value
Age (per 5 years) −0.019 0.05 −0.015 0.10 −0.020 <0.001 −0.0075 0.01
Log serum lutein [microg/ml] at follow-up −0.008 0.69 +0.013 0.41 +0.016 <0.01 +0.023 <0.001
Log serum zeaxanthin [microg/ml] at follow-up −0.01 0.73 −0.009 0.70 −0.006 0.74 −0.004 0.67
AMD (vs. none) at baseline −0.006 0.75 −0.010 0.51 −0.007 0.55 +0.002 0.86
MPOD Ring (vs. none) at baseline +0.024 0.24 +0.009 0.57 +0.013 0.31 +0.013 0.06
  1. * Adjusted—in addition to variables in table—for sex, body mass index and carotenoid supplementation, pseudophakia and spherical equivalent