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Table 3 Predictors of the change of MPOD (ΔMPOD) after a median follow-up of 3.96 years; the results are presented as regression coefficients (β) from multivariate regression models

From: Changes of macular pigment optical density in elderly eyes: a longitudinal analysis from the MARS study

 

Change of MPOD (ΔMPOD)*

At 0.25°

At 0.5°

At 1.0°

At 2.0°

Predictors

β

p value

β

p value

β

p value

β

p value

Age (per 5 years)

−0.019

0.05

−0.015

0.10

−0.020

<0.001

−0.0075

0.01

Log serum lutein [microg/ml] at follow-up

−0.008

0.69

+0.013

0.41

+0.016

<0.01

+0.023

<0.001

Log serum zeaxanthin [microg/ml] at follow-up

−0.01

0.73

−0.009

0.70

−0.006

0.74

−0.004

0.67

AMD (vs. none) at baseline

−0.006

0.75

−0.010

0.51

−0.007

0.55

+0.002

0.86

MPOD Ring (vs. none) at baseline

+0.024

0.24

+0.009

0.57

+0.013

0.31

+0.013

0.06

  1. * Adjusted—in addition to variables in table—for sex, body mass index and carotenoid supplementation, pseudophakia and spherical equivalent