Fig. 4

Multimodal imaging of the right eye of a 76-year-old Black female with polypoidal choroidal vasculopathy (PCV) who was followed for 56 months. Best corrected visual acuity (BCVA) upon initial diagnosis with PCV was 20/125 (61 letters), and worsened to counting fingers at last follow up visit. Treatment included 6 intravitreal injections with ranibizumab. Indocyanine green angiography image is showing late choroidal staining consistent with polypoidal lesions within the macula and nasal to the optic nerve. Upper row: Indocyanine green angiography imaging demonstrated macular and extramacular polypoidal lesions. Lower row: Color fundus photograph shows orange subretinal nodule, intraretinal and subretinal hemorrhage. Optical coherence tomography cross sectional B-scan through the macular polypoidal lesions (upon presentation) is demonstrating a large serous pigment epithelial detachment (PED) within the macula with associated subretinal fluid temporally and small temporal notch