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Table 1 Systemic history of patients studied

From: Macular edema is a rare finding in untreated vitreoretinal lymphoma: small case series and review of the literature

Patient

Sex

Systemic disease

VRL type

CNS type

Age at CNS-L dx

CT as only ttx

CT previous WBRT

Latency from CT to WBRT

WBRT

cGY

Latency from WBRT to VRL

Post CT

Last dose of CT

CT in VRL dx

CNS involves. at VRL dx

1

M

No

S

CNS-L

50

HD-MTX

2 months

Brain ON

3600 Brain 2520 ON

8 months

No

10 months

No

Yes

2

F

No

P

CNS-L

72

No

No

3

F

HBP

S

CNS-L

65

CHOP

2 months

Yes

?

36 months

No

29 months

No

No

4

M

Spindle cell sarcoma

S

DLCB

58

CHOP

?

Yes

?

132 months

MTX RT

ICE

Yes

No

5

M

Steven Johnson

S

CNS-L

63

CHOP, RT

10 months

Yes

?

16 months

No

27 months

No

Yes

6

F

HBP; Breast cancer

S

CNS-L

67

HD-MTX

3 months

No

Yes

7

F

HBP

P

CNS-L

61

HD-MTX

Steroids

Yes

Yes

8

F

HBP;DSL;HA; prostate cancer

P

CNS-L

73

Steroids

Yes

Yes

9

M

HA

S

CNS-L

79

CHOP MTX

36 months

No

Yes

  1. The dose and tissue irradiated was only known in one patient because the other patients were treated outside Mayo Clinic, and no reports were available
  2. HBP high blood pressure, DSL dyslipidemia, HA heart attack, P primary, S secondary, CNS-L central nervous system lymphoma, DX diagnosis, TTx treatment, CT chemotherapy, HD-MTX high-dose methotrexate, MTX methotrexate, RT rituximab, T temozolomide, CHOP cyclophosphamide plus hydroxydaunorubicin plus vincristine plus prednisone, ICE ifosfamide plus carboplatin plus etoposide, WBRT whole-brain radiotherapy