Table 1 Demographic variables and percentage and characteristics of segmentation errors identified using the ganglion cell algorithm analysis in macular diseases and healthy eyes

N (eyes)

30

30

15

15

15

15

15

Age (years)

56.3 ± 4.5

31.1 ± 11.81

37.6 ± 9.74

62.49 ± 11.49

68.0 ± 7.7

58.0 ± 14.2

53.6 ± 15.4

Mean signal strength

6.76 ± 0.81

8.36

8.17

6.60

6.80

6.46

6.86

Mean number of scans with error in one eye

35.84

122.9

52.6

20.5

61.5

75.8

25.26

Mean overall number of scans with errors (%)

26.8

95.5

41.0

20.5

48.0

64.47

19.7

Affected zone (%)

 Upper (1st–41st)

20

31.27

9.27

6.92

14.16

18.54

6.30

 Central (42nd–84th)

30

31.32

16.04

9.01

18.33

25.98

5.20

 Lower (85th–125th)

47

33.43

15.78

4.58

15.62

19.94

8.22

Affected scan area (%)

 Nasal 2500 μm

11.2

94.27

43.07

39.33

56.39

45.29

88.65

 Central

16.8

86.06

79.48

46.15

77.42

85.02

88.15

 Temporal 2500 μm

11.4

91.40

75.78

37.52

58.56

42.66

77.00

Layer affected (%)

 Inner

62

1.0

0.76

15.48

0

8.64

30.07

 Outer

17.2

0.02

12.29

3.55

20.82

6.70

0

 Both

20.79

99.59

86.94

80.96

78.95

84.65

69.92

Deviation (%)

 Upward

47.91

92.16

85.93

93.90

73.86

84.65

66.49

 Downward

33.43

23.56

17.36

6.09

26.35

15.58

0

 Both

18.65

2.52

0

0

0

0

33.50

Degree of deviation (%)

 Mild

38.6

77.81

88.97

94.41

98.59

94.91

96.04

 Moderate

20.9

14.31

11.02

3.80

2.49

4.52

3.95

 Severe

40.3

9.49

0

2.02

0

0.56

0

Type (%)

 Segmentation error

20.79

95.8

40.0

20.5

48.0

58.0

16

 Segmentation loss

2.91

0.0.78

1.1

0.8

1

1.2

2

 Defocus

6.70

4.4

0

0

0

0

0

 Out-of-register

3.3

10.9

0

0

0

0

0

 Shadowing

0

0.4

0

0

0

0

0

 Mirror artifact

0

4.5

0

0

0

0

0

 Blink artifact

0.09

0.4

0

0

0

0

0

Artifacts on IR image  (%)

 Motion

53.3

33.33

6.6

20

26

23

6.6

 Blink

0.09

6.66

0

0

0

0

0