Table 3 Summarized results of different studies comparing choroidal thickness measurements of healthy pregnant and non-pregnant women using EDI-OCT
From: Comparative analysis of choroidal thickness in third trimester pregnant women
References | Subjects | Gestational age at exam | Mean subfoveal choroidal thickness (SFCT) | Conclusion |
|---|---|---|---|---|
Takahashi et al. [27] | 30 pregnant women 30 non-pregnant women | Third trimester | 275 ± 84 µm 273 ± 92 µm | No significant difference in choroidal thickness between groups (p = 0.925) |
Sayin et al. [25] | 46 pregnant women 40 non-pregnant women | Variable 28.0 ± 5.8 weeks (range: 17–37 weeks) | 368.6 ± 67.6 µm 334.8 ± 59.9 µm | SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p = 0.038) |
Kara et al. [24] | 100 pregnant women 100 non-pregnant women | Variable 27.3 ± 6.6 weeks (range: 15–38 weeks) | 371.1 ± 61.8 µm 337.2 ± 62.4 µm | SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.01) |
Atas et al. [26] | 25 pregnant women 26 non-pregnant women | Over 28 weeks | 387.2 ± 60.76 µm 322.35 ± 63.89 µm | SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.001) |
Goktas et al. [29] | 30 pregnant women in the first trimester 30 pregnant women in the second trimester 30 pregnant women in the third trimester 30 non-pregnant women | First trimester Second trimester Third trimester | 362 ± 81 µm 395 ± 80 µm 368 ± 70 µm 335 ± 86 µm | SFCT was significantly thicker in pregnant women in the second trimester (p = 0.007) |
Ulusoy et al. [16] | 29 pregnant women 36 non-pregnant women | Third trimester 3 months after delivery | 387.97 ± 59.91 µm 332.40 ± 26.02 µm 320.86 ± 59.18 µm | SFCT significantly increases during pregnancy and returns to normal range 3 months after delivery |
Kim et al. [21] | 14 pregnant women 21 non-pregnant women | Third trimester | 274.23 ± 29.30 µm 264.95 ± 21.03 µm | No significant difference in choroidal thickness between groups (p = 0.325) |
Dadaci et al. [30] | 27 pregnant women 25 non-pregnant women | First trimester Third trimester | OD: 349.22 ± 82.11 µm OE: 341.30 ± 85.22 µm OD: 333.56 ± 76.61 µm OE: 326.93 ± 75.84 µm OD: 318.88 ± 53.13 µm OE: 310.60 ± 51.09 µm | Choroidal thickness measurements in the third trimester were significantly decreased in both eyes compared to first trimester measurements |
Rothwell et al. [31] | 12 pregnant women 12 non-pregnant women | Third trimester | 319.58 ± 6.11 µm 287.58 ± 43.44 µm | Choroidal thickness in normal pregnant women was significantly thicker than in non-pregnant healthy women (p = 0.034) |
Acmaz et al. [32] | 24 pregnant women 38 non-pregnant women | After 24 weeks | 393.77 ± 61.83 µm 322.49 ± 65.58 µm | Choroidal thickness in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.001) |