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Table 3 Summarized results of different studies comparing choroidal thickness measurements of healthy pregnant and non-pregnant women using EDI-OCT

From: Comparative analysis of choroidal thickness in third trimester pregnant women

References Subjects Gestational age at exam Mean subfoveal choroidal thickness (SFCT) Conclusion
Takahashi et al. [27] 30 pregnant women
30 non-pregnant women
Third trimester 275 ± 84 µm
273 ± 92 µm
No significant difference in choroidal thickness between groups (p = 0.925)
Sayin et al. [25] 46 pregnant women
40 non-pregnant women
Variable
28.0 ± 5.8 weeks
(range: 17–37 weeks)
368.6 ± 67.6 µm
334.8 ± 59.9 µm
SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p = 0.038)
Kara et al. [24] 100 pregnant women
100 non-pregnant women
Variable
27.3 ± 6.6 weeks
(range: 15–38 weeks)
371.1 ± 61.8 µm
337.2 ± 62.4 µm
SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.01)
Atas et al. [26] 25 pregnant women
26 non-pregnant women
Over 28 weeks 387.2 ± 60.76 µm
322.35 ± 63.89 µm
SFCT in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.001)
Goktas et al. [29] 30 pregnant women in the first trimester
30 pregnant women in the second trimester
30 pregnant women in the third trimester
30 non-pregnant women
First trimester
Second trimester
Third trimester
362 ± 81 µm
395 ± 80 µm
368 ± 70 µm
335 ± 86 µm
SFCT was significantly thicker in pregnant women in the second trimester (p = 0.007)
Ulusoy et al. [16] 29 pregnant women
36 non-pregnant women
Third trimester
3 months after delivery
387.97 ± 59.91 µm
332.40 ± 26.02 µm
320.86 ± 59.18 µm
SFCT significantly increases during pregnancy and returns to normal range 3 months after delivery
Kim et al. [21] 14 pregnant women
21 non-pregnant women
Third trimester 274.23 ± 29.30 µm
264.95 ± 21.03 µm
No significant difference in choroidal thickness between groups (p = 0.325)
Dadaci et al. [30] 27 pregnant women
25 non-pregnant women
First trimester
Third trimester
OD: 349.22 ± 82.11 µm
OE: 341.30 ± 85.22 µm
OD: 333.56 ± 76.61 µm
OE: 326.93 ± 75.84 µm
OD: 318.88 ± 53.13 µm
OE: 310.60 ± 51.09 µm
Choroidal thickness measurements in the third trimester were significantly decreased in both eyes compared to first trimester measurements
Rothwell et al. [31] 12 pregnant women
12 non-pregnant women
Third trimester 319.58 ± 6.11 µm
287.58 ± 43.44 µm
Choroidal thickness in normal pregnant women was significantly thicker than in non-pregnant healthy women (p = 0.034)
Acmaz et al. [32] 24 pregnant women
38 non-pregnant women
After 24 weeks 393.77 ± 61.83 µm
322.49 ± 65.58 µm
Choroidal thickness in normal pregnant women was significantly thicker than in non-pregnant healthy women (p < 0.001)