From: Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study
Risk factors | ROP | Without ROP | P |
---|---|---|---|
n = 204 (33.9%) | n = 398 (66.1%) | ||
Male, n (%) | 101 (49.5%) | 201 (50.5%) | .689a |
Type of birth, n (%) | .832a | ||
Singleton | 169 (82.8%) | 326 (81.9%) | |
Twin or multiple | 35 (17.2%) | 72 (18.1%) | |
Sepsis, n (%) | 167 (83.5%)**** | 285 (71.6%) | .001a |
Use of surfactants, n (%) | 179 (88.6%)** | 258 (65%)* | < .001a |
Intraventricular hemorrhage, n (%) | 54 (26.7%)** | 50 (12.6%) | < .001a |
Erythropoietin, n (%) | 16 (7.9%)** | 12 (3%) | .006a |
Maternal use of antenatal corticosteroids, n (%) | 58 (28.7%)** | 44 (11.1%) | < .001a |
Cardiac diseases, n (%) | 69 (33.8%) | 51 (12.8%) | < .001a |
Pulmonary diseases, n (%) | 171 (83.8%) | 250 (62.8%) | < .001a |
Digestive diseases, n (%) | 11 (5.4%) | 16 (4%) | .577a |
Birth weight < 1000 g, n (%) | 98 (48.0%) | 50 (12.6%) | < .001a |
Gestational age (weeks), mean ± SD | 29.4 (2.5) | 31.4 (2.2) | < .001b |
Apgar score at 1 min, mean ± SD | 6 (2.3) | 6.7 (2.2) | .001b |
Apgar score at 5 min, mean ± SD | 7.7 (1.4) | 8.2 (1.5) | < .001b |
Days on oxygen therapy, median (minimum to maximum) | 27 (0–150) | 6 (0–150) | < .001c |
Days on CPAP, median (minimum to maximum) | 4 (0–42) | 2 (0–30) | < .001c |
Days on mechanical ventilation, median (minimum–maximum) | 7 (0–103) | 1 (0–150) | <.001 |
Number of blood transfusions, median (minimum to maximum) | 1 (0–15) | 0 (0–12) | < .001 |