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Table 4 Studies on the incidence and risk factors for ROP

From: Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study

Author

Country

Year of publication

Study design

Patients (n)

Inclusion criteria

Incidence of any stage ROP (%)

Main risk factors

Schaffer et al. (CRYO-ROP Study) [31]

United States

1993

MRCT

4099

BW < 1251 g

66.0

GA, BW, multiple births, Out of nursery birth, white race

Good et al. (ET-ROP Study) [16]

United States

2004

MRCT

6998

BW < 1251 g

68.0

NR

Fortes Filho et al. [4]

Brazil

2009

PCS

450

BW < 1500 g or GA < 32 w

24.2

GA, BW, PMV, sepsis, IVH, BT

Zin et al. [23]

Brazil

2010

PCS

3437

BW < 2000 g or GA <  37 w

19.9

NR

Lomuto et al. [32]

Argentina

2010

RCS

956

BW < 1500 g or GA < 32 w

26.2

NR

Gonçalves et al. [11]

Brazil

2014

PCS

110

BW < 1500 g or GA < 32 w

44.5

GA, BW, BT, sepsis

Mitsiakos et al. [33]

Canada

2016

RCS

1562

GA < 32 w

15.6

BW, sepsis, NEC, PDA, PMV

Yau et al. [34]

China

2016

RCS

513

BW < 1500 g or GA < 32 w

18.5

GA, BW, IVH

Owen et al. [35]

United States

2017

RCS

457

BW < 1250 g or GA < 30 w

47.5

GA, BW, maternal Mg prophylaxis, need of any surgery

Ahuja et al. [36]

India

2018

PCS

325

BW < 1900, GA <  36 w

32.6

BW

Bas et al. [37]

Turkey

2018

PCS

6115

BW < 1500 g, or GA < 32 w, or unstable clinical course

27.0

GA, BW, days on oxygen, sepsis, BT, relative weight gain

  1. ROP retinopathy of prematurity, MRCT multicenter randomized clinical trial, PCS prospective cohort study, RCS retrospective cohort study, g grams, w weeks, NR not reported, GA gestational age, BW birth weight, PMV prolongued mechanical ventilation, IVH intraventricular hemorrhage, BT blood transfusions, NEC necrotizing enterocolitis; PDA persistent ductus arteriosus, Mg magnesium