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Table 1 Vascular density and blood flow of the retinal capillary networks and choriocapillaris in eyes with central retinal vein occlusion (case) compared to fellow eyes of patients and healthy eyes (control)

From: Quantitative measurement of vascular density and flow using optical coherence tomography angiography (OCTA) in patients with central retinal vein occlusion: Can OCTA help in distinguishing ischemic from non-ischemic type?

  Groups Mean ± SD (range) P1 P2 P3
Case Fellow eye Control
Flow in superficial capillary network in 3 × 3 mm image 1.171 ± 0.262 1.362 ± 0.285 1.453 ± 0.105 < 0.001 0.003 0 < .001 0.183
  (0.426–1.583) (0.455–1.949) (1.159–1.625)     
Flow in deep capillary network in 3 × 3 mm image 1.042 ± 0.402 1.331 ± 0.315 1.526 ± 0.123 < 0.001 0.001 0 < .001 0.024
  (0.164–1.55) (0.371–1.657) (1.152–1.673)     
Flow in choriocapillaris in 3 × 3 mm image 1.206 ± 0.543 1.841 ± 0.308 1.966 ± 0.05 < 0.001 0 < .001 0 < .001 0.274
  (0.212–1.961) (0.466–2.056) (1.833–2.059)     
Whole vascular density of superficial capillary network 45.92 ± 4.2 50.99 ± 4.35 52.85 ± 2.99 < 0.001 0 < .001 0 < .001 0.069
  (38.93–57.95) (39.24–57.34) (47.59–57.57)     
Foveal vascular density of superficial capillary network 36.47 ± 9.78 30.13 ± 7.12 30.63 ± 6.44 < 0.001 0.003 0.018 0.824
  (22.53–65.34) (19.4–54.78) (13.29–42.25)     
Parafoveal vascular density of superficial capillary network 47.04 ± 5 52.91 ± 4.79 55.01 ± 3.45 < 0.001 0 < .001 0 < .001 0.062
  (37.3–61.39) (41.27–58.92) (48.02–59.5)     
Parafoveal vascular density of superficial capillary network in temporal area 44.75 ± 5.66 51.19 ± 6.11 53.7 ± 2.76 < 0.001 0 < .001 0 < .001 0.066
  (28.03–59.48) (36.89–58.63) (47.1–57.78)     
Parafoveal vascular density of superficial capillary network in superior area 47.37 ± 5.67 53.97 ± 4.7 55.76 ± 3.39 < 0.001 0 < .001 0 < .001 0.169
  (36.29–64.65) (40.92–60.37) (49.17–60.31)     
Parafoveal vascular density of superficial capillary network in nasal 48.09 ± 4.39 52.54 ± 5.03 53.92 ± 5.92 < 0.001 0.001 0 < .001 0.321
  (40.79–57.97) (39.17–59.88) (33.43–59.36)     
Parafoveal vascular density of superficial capillary network in inferior part 47.34 ± 7.08 53.52 ± 5.33 56.01 ± 3.89 < 0.001 0 < .001 0 < .001 0.169
  (32.56–63.46) (40.75–60.45) (48.54–61.06)     
Whole vascular density of deep capillary network 48.03 ± 4.71 55.86 ± 3.81 58.2 ± 2.65 < 0.001 0 < .001 0 < .001 0.857
  (39.8–59.3) (46.59–60.07) (52.2–63.1)     
Foveal vascular density of deep capillary network 34.15 ± 12.36 27.54 ± 6.44 28.99 ± 7.97 < 0.001 0 < .001 0 < .001 0.049
  (11.31–59.44) (11.85–39.58) (10.2–46.4)     
Parafoveal vascular density of deep capillary network 49.65 ± 5.4 58.35 ± 4.01 60.87 ± 3.55 < 0.001 0.005 0.045 0.559
  (37.89–62.66) (48.55–63.47) (50.87–68.2)     
Parafoveal vascular density of deep capillary network in temporal part 48.1 ± 6.59 55.92 ± 6.73 60.07 ± 3.18 < 0.001 0 < .001 0 < .001 0.011
  (32.27–61.94) (36.15–64.19) (53.44–67.18)     
Parafoveal vascular density of deep capillary network in superior part 49.94 ± 7.06 60.1 ± 4.82 62.53 ± 2.41 < 0.001 0 < .001 0 < .001 0.096
  (36.26–65.68) (48.65–68.04) (58.51–67.45)     
Parafoveal vascular density of deep capillary network in nasal part 50.88 ± 5.92 57.79 ± 5.36 58.52 ± 8.47 < 0.001 0 < .001 0.001 0.942
  (32.25–59.86) (41.73–67.55) (26.4–66.45)     
Parafoveal vascular density of deep capillary network in inferior part 49.05 ± 8.4 58.72 ± 5.09 62.75 ± 2.85 < 0.001 0 < .001 0 < .001 0.009
  (28.26–64.84) (47.57–65.43) (58.13–68.39)     
Flow in superficial capillary network in 8 × 8 mm image 10.952 ± 1.846 11.77 ± 1.497 12.591 ± 1.035 0.001 0.089 0 < .001 0.030
  (5.9–13.76) (7.641–13.841) (10.641–14.655)     
Flow in deep capillary network in 8 × 8 mm image 7.907 ± 3.155 10.449 ± 3.124 12.576 ± 1.742 < 0.001 0.002 0 < .001 0.004
  (1.452–13.215) (3.517–14.988) (9.874–15.157)     
Flow in choriocapillaris in 8 × 8 mm image 11.543 ± 4.802 16.757 ± 2.669 17.486 ± 0.414 < 0.001 0 < .001 0 < .001 0.392
  (1.443–17.378) (2.828–17.987) (16.393–18.344)     
  1. Based on GEE, SD standard deviation; p value among three groups; P1 p value between case and fellow eye; P2 p value between case and control; P3 p value between fellow eye and control