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Table 1 Demographic, clinical, OCT, topographic and color doppler parameter levels (Mean ± SE) of four groups

From: Resistive index of central retinal artery is a bioimaging biomarker for severity of diabetic retinopathy

Variables Controls (n = 26) (%) NO DR (n = 26) (%) NPDR (n = 29) (%) PDR (n = 26) (%) F/χ2 value p value
Age (yrs) 60.45 ± 1.43 60 ± 1.54 58.33 ± 2.32 63.89 ± 1.95 1.58 0.265
Sex
 Female 10 (36.4) 11 (40.9) 9 (28.0) 7 (22.7) 2.20 0.587
 Male 16 (63.6) 15 (59.1) 20 (72.0) 19 (77.3)   
HbA1c (%) 5.41 ± 0.12 7.94 ± 0.21 8.50 ± 0.295 8.84 ± 0.167 55.87 <0.001
S. urea (mg/dl) 33.278 ± 0.854 38.078 ± 2.154 37.87 ± 0.978 39.84 ± 1.13 4.31 0.008
S. creatinine (mg/dl) 0.98 ± 0.02 1.16 ± 0.03 1.15 ± 0.03 1.64 ± 0.07 46.546 <0.001
VA (LogMAR) 0.089 ± 0.02 0.36 ± 0.14 0.76 ± 0.07 1.16 ± 0.02 109.76 <0.001
CST (μm) 246.91 ± 2.62 267.73 ± 4.37 308.72 ± 22.52 456.91 ± 19.36 37.21 <0.001
CAT (μm) 255.67 ± 1.08 273.44 ± 7.57 301.06 ± 9.37 371.26 ± 6.23 50.675 <0.001
RNFL (μm) 89.38 ± 0.33 85.57 ± 0.89 86.06 ± 0.92 72.35 ± 1.37 61.14 <0.001
EZ
 Disruption absent 26 (100.0) 23 (95.5) 24 (56.0) 0 (0.0) 60.66 <0.001
 Disruption present 0 (0.0) 3 (4.5) 5 (44.0) 26 (100.0)   
RI-CRA 0.66 ± 0.01 0.77 ± 0.01 0.79 ± 0.02 0.987 ± 0.09 10.24 <0.001
  1. NO DR no diabetic retinopathy, NPDR non proliferative diabetic retinopathy, PDR proliferative diabetic retinopathy, BCVA best corrected visual acuity, HBA1c glycosylated haemoglobin, CST central subfield thickness, CAT cube average thickness, RNFL retinal nerve fiber layer, EZ ellipsoid zone, RI-CRA resistive index of central retinal artery