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Table 2 Diagnostic accuracy of RI-CRA to discriminate controls and cases using ROC curve analysis

From: Resistive index of central retinal artery is a bioimaging biomarker for severity of diabetic retinopathy

Group Criterion (cut off) value Sensitivity (95% CI Specificity (95% CI) +PV −PV AUC Z value p value
NO DR > 0.68 100.00 (84.4–100.0) 95.45 (77.1–99.2.) 95.7 100.0 0.999 100.69 < 0.001
NPDR > 0.69 76.00 (54.9–90.6) 100.00 (84.4–100.0) 100.0 78.6 0.841 5.87 < 0.001
PDR > 0.69 95.45 (77.1–99.2) 100.00 (84.4–100.0) 100.0 95.7 0.955 13.76 < 0.001
Total > 0.69 88.41 (78.4–94.8) 100.00 (84.4–100.0) 100.0 73.3 0.928 16.22 < 0.001
  1. +PV, positive predictive value; −PV, negative predictive value; AUC, area under the curve; NA, not applicable, NO DR no diabetic retinopathy, NPDR non proliferative diabetic retinopathy, PDR proliferative diabetic retinopathy