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Table 2 Diagnostic accuracy of RI-CRA to discriminate controls and cases using ROC curve analysis

From: Resistive index of central retinal artery is a bioimaging biomarker for severity of diabetic retinopathy

Group

Criterion (cut off) value

Sensitivity (95% CI

Specificity (95% CI)

+PV

−PV

AUC

Z value

p value

NO DR

> 0.68

100.00 (84.4–100.0)

95.45 (77.1–99.2.)

95.7

100.0

0.999

100.69

< 0.001

NPDR

> 0.69

76.00 (54.9–90.6)

100.00 (84.4–100.0)

100.0

78.6

0.841

5.87

< 0.001

PDR

> 0.69

95.45 (77.1–99.2)

100.00 (84.4–100.0)

100.0

95.7

0.955

13.76

< 0.001

Total

> 0.69

88.41 (78.4–94.8)

100.00 (84.4–100.0)

100.0

73.3

0.928

16.22

< 0.001

  1. +PV, positive predictive value; −PV, negative predictive value; AUC, area under the curve; NA, not applicable, NO DR no diabetic retinopathy, NPDR non proliferative diabetic retinopathy, PDR proliferative diabetic retinopathy