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Table 2 Results of multivariable regression models—dependent variable: pRNFL thickness

From: Neurodegeneration in systemic lupus erythematosus: layer by layer retinal study using optical coherence tomography

Model

Coefficient estimate

95% confidence interval

p-value

Dependent variable: pRNFL thickness G

 SLE group*

− 3.87

− 7.27 to − 0.48

0.026

 Male sex

− 4.93

− 9.39 to − 0.46

0.031

 Age (years)

− 2.60

− 3.87 to − 1.32

< 0.001

 Axial length (mm)

− 2.23

− 3.97 to − 0.49

0.013

 Benzodiazepines

7.37

1.70 to 13.04

0.011

Dependent variable: pRNFL thickness TS

 SLE group*

− 7.94

− 13.64 to − 2.38

0.007

Dependent variable: pRNFL thickness T

 SLE group*

− 4.14

− 8.03 to − 0.25

0.037

Dependent variable: pRNFL thickness TI

 SLE group*

− 3.95

− 11.17 to 3.28

0.282

 Age (years)

− 3.28

− 5.86 to − 0.69

0.013

Dependent variable: pRNFL thickness NI

 SLE group*

6.39

− 2.59 to 15.36

0.161

 Axial length (mm)

− 5.91

− 10.21 to − 1.61

0.007

Dependent variable: pRNFL thickness N

 SLE group*

− 2.42

− 6.94 to 2.10

0.291

 Age (years)

− 1.86

− 3.47 to − 0.24

0.025

Dependent variable: pRNFL thickness NS

 SLE group*

− 7.04

− 14.53 to 0.46

0.065

 Age (years)

− 3.40

− 6.08 to − 0.72

0.013

  1. *Reference category: control group. Age: for each 10-year increase. p-values were obtained by linear regression models
  2. G global, N nasal, NI nasal inferior, NS nasal superior, pRNFL peripapillary retinal nerve fiber layer, SLE systemic lupus erythematosus, T temporal, TI temporal inferior, TS temporal superior