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Table 3 Results of multivariable regression models for the SLE group—dependent variable: pRNFL thickness

From: Neurodegeneration in systemic lupus erythematosus: layer by layer retinal study using optical coherence tomography

ModelCoefficient estimate95% confidence intervalp-value
Dependent variable: pRNFL thickness G
 Age (years)− 3.02− 4.91 to − 1.130.002
 Axial length (mm)− 3.98− 6.34 to − 1.620.001
 Calcium channel blocker− 10.66− 18.56 to − 2.770.009
 Anticoagulant− 6.71− 12.42 to − 1.000.022
Dependent variable: pRNFL thickness TS
 Age (years)− 3.38− 6.55 to − 0.220.037
 Axial length (mm)− 4.12− 8.13 to − 0.120.044
Dependent variable: pRNFL thickness T
 Sjogren syndrome− 10.36− 19.38 to − 1.350.025
Dependent variable: pRNFL thickness TI
 IOP (mm Hg)− 2.15− 3.60 to − 0.710.004
 Calcium channel blocker− 17.97− 32.64 to − 3.300.017
 Anticoagulant− 15.08− 25.84 to − 4.310.007
 Statin− 13.94− 25.73 to − 2.150.021
Dependent variable: pRNFL thickness NI
 Axial length (mm)− 9.03− 14.59 to − 3.470.002
 Anticoagulant− 17.16− 31.56 to − 2.760.020
 Statin− 18.56− 34.09 to − 3.030.020
Dependent variable: pRNFL thickness N
 Body mass index (kg/m2)− 0.80− 1.58 to − 0.010.046
 ACE inhibitor− 10.03− 18.61 to − 1.450.023
Dependent variable: pRNFL thickness NS
 Axial length (mm)− 5.47− 9.46 to − 1.470.008
 Calcium channel blocker− 20.07− 34.01 to − 6.120.006
 Anticoagulant− 11.34− 21.99 to − 0.690.037
 Corticosteroid (mg)0.120.05 to 0.180.001
  1. Age: for each 10-year increase. Corticosteroid is expressed as the daily dose of prednisone equivalent. p-values were obtained by linear regression models
  2. ACE angiotensin-converting enzyme, G global, IOP intraocular pressure, N nasal, NI nasal inferior, NS nasal superior, pRNFL peripapillary retinal nerve fiber layer, SLE systemic lupus erythematosus, T temporal, TI temporal inferior, TS temporal superior