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Table 5 Results of multivariable regression models for PR layer thickness in the SLE group

From: Neurodegeneration in systemic lupus erythematosus: layer by layer retinal study using optical coherence tomography

Model*

Coefficient estimate

95% confidence interval

p-value

Dependent variable: PR layer thickness at C sector

 NP-SLE

− 2.83

− 5.29 to − 0.37

0.025

 Sjogren’s syndrome

5.05

0.71 to 9.40

0.023

 SLEDAI

− 0.29

− 0.51 to − 0.06

0.015

 Body mass index (kg/m2)

− 0.31

− 0.60 to − 0.02

0.038

Dependent variable: PR layer thickness at S3 sector

 Benzodiazepine

2.67

0.35 to 4.99

0.025

Dependent variable: PR layer thickness at T3 sector

 Calcium channel blocker

− 2.68

− 5.23 to − 0.14

0.039

Dependent variable: PR layer thickness at I3 sector

 Statin

− 1.84

− 3.48 to − 0.20

0.028

Dependent variable: PR layer thickness at N3 sector

 Sjogren’s syndrome

2.38

0.2 to 4.74

0.048

 SLEDAI

− 0.13

− 0.26 to 0.00

0.050

 Statin

− 2.44

− 4.15 to − 0.73

0.006

Dependent variable: PR layer thickness at S6 sector

 Benzodiazepine

1.95

0.23 to 3.68

0.027

 HCQ treatment time (years)

− 0.83

− 0.16 to 0.00

0.041

Dependent variable: PR layer thickness at N6 sector

 Axial length (mm)

0.53

0.01 to 1.05

0.045

 ACE inhibitor

− 1.50

− 2.95 to − 0.05

0.043

  1. No multiple model was achieved for the T6 and I6 sectors. p-values were obtained by linear regression models
  2. ACE angiotensin-converting enzyme, HCQ hydroxychloroquine, NP-SLE neuropsychiatric systemic lupus erythematosus, PR photoreceptor, SLEDAI Systemic Lupus Erythematosus Disease Activity Index