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Table 1 Baseline characteristics of the study patients

From: Visual and anatomic outcomes of sustained single agent anti-VEGF treatment versus double anti-VEGF switching in the treatment of persistent diabetic macular edema

 

Group 1

Group 2

p-value

Subgroup 1A

Subgroup 1B

Age, mean (SD)

65.5 ± (10.4)

63.6 ± (7.1)

72.5 ± (8.1)

0.005**

Sex

 Female

13 (54.2%)

6 (33.3%)

5 (35.7%)

0.267

 Male

11 (45.8%)

12 (66.7%)

9 (64.3%)

Type of DM

 Type 1

5 (20.9%)

4 (22.2%)

2 (14.3%)

0.82

 Type 2

19 (79.1%)

14 (77.8%)

12 (85.7%)

Last known HBA1C, mean (SD)

7.2 ± (0.8)

7.5 ± (1.5)

7.5 ± (1.2)

0.91

Insulin use (%)

17 (70.8%)

12 (66.7%)

8 (57.1%)

0.89

Anti-VEGF treatment Naïve eyes (%)

14 (58.3%)

9 (50%)

9 (64.2%)

0.71

Prior focal laser treatment (%)

10 (41.6%)

6 (33.3%)

7 (50%)

0.64

Prior PRP treatment (%)

5 (20.8%)

2 (11.1%)

0 (0%)

0.17

Baseline logMAR VA, mean (SD)

0.58 ± (0.29)

0.65 ± (0.34)

0.55 ± (0.24)

0.87

Baseline CRT measurement (µm) (SD)

445.92 ± (126.4)

537.72 ± (131.7)

410.87 ± (86.4)

0.011*

  1. PRP panretinal photocoagulation, CRT central retinal subfield thickness
  2. *Group 1B patients had significantly thicker baseline CRT than other two groups. All other baseline demogrpgic data were not different between all groups
  3. **Group 2 patients had significantly older age than other groups