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Fig. 3 | International Journal of Retina and Vitreous

Fig. 3

From: Safety and tolerability evaluation after repeated intravitreal injections of a humanized anti-VEGF-A monoclonal antibody (PRO-169) versus ranibizumab in New Zealand white rabbits

Fig. 3

ERG analysis of NZW rabbits as a function of time after intravitreal injections. a The effects of the intravitreal PRO-169 (white bars) and ranibizumab (dark bars) on the dark-adapted ERG responses after 30 days of each injection. The dark-adapted retinal response is represented by the mean ± SEM VMax ratio of the ERG (b-wave). b Time dependent effects of repeated injections of PRO-169 and ranibizumab on retinal function of rabbits. The difference of the log semi saturation constant (experimental-control) is represented by the mean ± SEM. VMax ratios are around 1 and log σ differences are around 0, indicating no damage to the road system

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