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Fig. 5 | International Journal of Retina and Vitreous

Fig. 5

From: Preclinical assessment of intravitreal ramucirumab: in vitro and in vivo safety profile

Fig. 5

Retinal findings by histology with hematoxylin and eosin staining seven days after intravitreal injection of ramucirumab. a control eye. bd IVT injection of 250 µg ramucirumab. eh IVT injection of 500 µg ramucirumab. Ganglion cells: focal areas of vacuolization (*). Inner plexiform and nuclear layers showing focal vacuolization. Outer plexiform layer: intact. Outer nuclear layer: artifactual findings (red arrows)

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