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Fig. 7 | International Journal of Retina and Vitreous

Fig. 7

From: Preclinical assessment of intravitreal ramucirumab: in vitro and in vivo safety profile

Fig. 7

Ultrastructural analysis of rabbit retinas treated with 500 µg ramucirumab at 24 h and seven days. ad Control. eh 24 h-treated retina. il 7 day-treated retina. All experimental conditions showed retinal layers with normal appearance, without signs of apoptosis. GCL ganglion cell layer, INL inner nuclear layer, ONL outer nuclear layer. In the inner photoreceptor segment (IS), notice the presence of mitochondria (Mi), while outer segment (OS) is characterized by the presence of disc membranes (*)

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