|
Variables
|
Initial disease (I or II)
|
Metastases (regional or distant)
|
Missing/do not apply
|
Total
|
p value
|
|---|
| |
Nc (%a)
|
Nc (%a)
|
Nc (%a)
|
Nc (%b)
| |
|
Year of diagnosisd
| | | | |
0.680
|
|
2000 a 2012
|
356 (20.1)
|
273 (15.4)
|
1138 (64.4)
|
1767 (81.6)
| |
|
2013 a 2016
|
73 (18.3)
|
61 (15.3)
|
265 (66.4)
|
399 (18.4)
| |
|
Time from diagnosis to treatment
| | | | |
0.005
|
|
≤ 60 days
|
236 (24.7)
|
183 (19.2)
|
535 (56.1)
|
954 (59.4)
| |
|
> 60 days
|
150 (23.0)
|
89 (13.7)
|
412 (63.3)
|
651 (40.6)
| |
|
No treatment
|
27
|
34
|
304
|
365
| |
|
Missing
|
16
|
28
|
152
|
196
| |
|
Response to the first course of treatmente
| | | | |
< 0.001
|
|
Response
|
43 (11.9)
|
28 (7.8)
|
290 (80.3)
|
361 (76.8)
| |
|
No response
|
4 (3.7)
|
29 (26.6)
|
76 (69.7)
|
109 (23.2)
| |
|
No treatment
|
27
|
34
|
304
|
365
| |
|
Missing
|
355
|
243
|
733
|
1331
| |
|
Total
|
429 (19.8)
|
334 (15.4)
|
1403 (64.8)
|
2166 (100.0)
| |
- aRow percent
- bColumn percent
- cDifferences in total are due to missing data; percentages were calculated considering only patients with available data
- dAccording to the federal law of 60 days that came into effect in 2013
- eResponse: partial remission, stable disease, and complete response; no response: progressive disease, relapsed disease or death
- Statistically significant associations are indicated in italics