Groups VD/ Reference group | NL (37 eyes) Mean ± SD (%) | NDR (35 eyes) Mean ± SD (%) | NPDR (58 eyes) Mean ± SD (%) | PDR (46 eyes) Mean ± SD (%) | p-value Kruskal–Wallis test |
---|---|---|---|---|---|
Whole image (median) NL NDR NPDR | 58.26 (53.54–61.60) | 56.90 (49.73–61.62) 0.145* | 55.11 (46.48–59.59) 0.014* 0.398* | 55.48 (49.94–55.48) < 0.001* 0.018* 0109* | 0.002 |
Whole disc NL NDR NPDR | 52.39 ± 0.96 | 53.15 ± 0.96 1.000 | 49.66 ± 1.90 0.746 0.767 | 50.03 ± 1.62 0.033 0.039 0.191 | 0.018 |
N-disc NL NDR NPDR | 50.35 ± 1.87 | 52.76 ± 1.37 0.958 | 50.23 ± 2.50 0.862 0.996 | 54.66 ± 2.30 0.995 0.869 0.683 | 0.684 |
IN-disc NL NDR NPDR | 56.74 ± 3.14 | 59.35 ± 2.10 0.582 | 54.33 ± 3.81 0.993 0.345 | 57.66 ± 2.24 0.833 0.136 0.913 | 0.182 |
IT-disc NL NDR NPDR | 52.35 ± 1.44 | 52.91 ± 1.94 0.869 | 45.51 ± 3.04 0.130 0.560 | 46.15 ± 2.75 0.024 0.823 0.823 | 0.022 |
T-disc NL NDR NPDR | 49.91 ± 1.80 | 48.34 ± 1.36 0.498 | 46.05 ± 2.05 0.145 0.945 | 41.25 ± 1.78 < 0.001 0.004 0.006 | < 0.001 |
ST-disc NL NDR NPDR | 51.47 ± 2.18 | 48.66 ± 2.11 0.648 | 46.92 ± 2.04 0.962 0.850 | 45.42 ± 2.70 0.463 0.997 0.679 | 0.426 |
SN-disc NL NDR NPDR | 57.13 ± 2.20 | 60.59 ± 2.25 0.419 | 57.10 ± 2.16 0.999 0.398 | 55.13 ± 2.45 0.996 0.260 0.981 | 0.272 |
Whole RPC NL NDR NPDR | 62.24 (56.78–67.02) | 59.68 (55.13–65.35) 0.006 | 60.07 (50.83–64.37) 0.009* 0.991* | 59.35 (51.42–65.48) < 0.001* 0.036* 0.041* | < 0.001* |
N-RPC NL NDR NPDR | 60.07 (53.26–67.12) | 57.33 (50.30–64.84) < 0.001* | 59.41 (36.69–53.39) 0.087* 0.631* | 58.66 (44.94–66.08) 0.001* 0.112* 0.073* | 0.011* |
IN-RPC NL NDR NPDR | 53.75 ± 1.00 | 60.22 ± 1.26 < 0.104 | 60.31 ± 2.01 0.031 0.997 | 60.81 ± 1.28 0.006 0.836 0.884 | 0.0001 |
IT-RPC NL NDR NPDR | 64.48 ± 0.92 | 63.64 ± 0.75 0.331 | 60.94 ± 1.21 0.006 0.486 | 61.11 ± 1.04 < 0.001 0.037 0.427 | < 0.001 |
T-RPC NL NDR NPDR | 62.45 ± 0.78 | 60.84 ± 0.73 0.648 | 58.95 ± 0.70 0.911 0.911 | 58.00 ± 1.86 < 0.001 0.030 0.072 | 0.001 |
ST-RPC NL NDR NPDR | 62.63 ± 1.07 | 61.45 ± 1.11 0.622 | 59.66 ± 2.16 0.993 0.993 | 55.13 ± 2.45 0.006 0.196 0.206 | 0.012 |
SN-RPC NL NDR NPDR | 62.34 (49.65–47.35) | 59.06 (50.16–59.06) 0.099 | 60.38 (55.23–68.06) 0.087 0.686* | 58.46 (35.64–68.39) 0.016 0.336* 0.517* | 0.047 |
Peripapillary CC flow (median) NL NDR NPDR | 7.57 (7.19–7.89) | 7.63 (6.81–7.84) 0.890* | 7.50 (1.74–8.80) 0.023* 0.024* | 7.43 (1.5–7.79) 0.003* 0.004* 0.283* | 0.003 |
Peripapillary CC flow- /area2 mm radius NL NDR NPDR | 0.61 (0.58–0.63) | 0.60 (0.56–0.62) 0.713* | 0.60 (0.52–0.62) 0.009* 0.016* | 0.59 (0.50–0.63) 0.001* 0.003* 0.482* | 0.001 |