Table 3 Univariate analysis and binary logistic regression analysis of factors influencing the peripheral events, extension of Main DME outside ETDRS and the presence of peripheral retinal edema
From: Large-cube 30° × 25° optical coherence tomography in diabetic macular edema
Presence of Peripheral events | Extension of Main DME outside ETDRS | Presence of Peripheral retinal edemas | ||||
|---|---|---|---|---|---|---|
Univariate analysis Coeff (p-value) † | Multivariate analysis Odds ratio [CI] (p value)‡ | Univariate analysis Coeff (p-value) † | Multivariate analysis Odds ratio [CI] (p value)‡ | Univariate analysis Coeff (p-value) † | Multivariate analysis Odds ratio [CI] (p value)‡ | |
Side | 0.01 (0.78) | 0/07 (0.14) | 0.08 (0.14) | |||
Age | 0.08 (0.08) | 0.06 (0.27) | 0.04 (0.39) | |||
Gender | 0.06 (0.24) | 0.07 (0.17) | 0.07 (0.16) | |||
Diabetes History | 0.02 (0.97) | 0.07 (0.18) | 0.02 (0.68) | |||
Diabetes Treatment | 0.10 (0.28) | 0.05 (0.79) | 0.07 (0.59) | |||
High Blood Pressure | 0.05 (0.77) | 0.02 (0.65) | 0.004 (0.94) | |||
HbA1C | 0.16 (0.007) | 253.5 [0.001– > 100] (0.54) | 0.18 (0.003) | > 100 [0.001–> 100] (0.188) | 0.10 (0.06) | |
Advanced DR Stage | 0.28 (< 0.001) | 2.19 [1.29–3.72] (0.03) | 0.36 (< 0.001) | 1.74 [1.06–2.87] (0.028) | 0.2 (0.01) | 1.42 [1.07–1.88] (0.014) |
CMT | 0.05 (0.31) | 0.16 (0.002) | 0.98 [0.97–0.99] (0.004) | 0.13 (0.008) | 0.98 [0.97–0.99] (0.005) | |
Diffuse DME Surface | 0.39 (< 0.001) | 7.76 [2.58–23.32] (< 0.001) | 0.55 (< 0.001) | 23.85 [7.59–74.98] (< 0.001) | 0.30 (< 0.001) | 1.74 [1.00–3.04] (0.027) |
Hard exudates | 0.16 (0.003) | 2.18 (0.77–6.13) (0.13) | 0.18 (< 0.001) | 4.83 [1.27–18.41] (0.021) | 0.13 (0.01) | 2.13 [1.05–4.31] (0.035) |
Microaneurysms | 0.007 (0.90) | 0.04 (0.44) | 0.07 (0.19) | |||
Large Cysts Size | 0.19 (0.039) | 1.62 (0.97–2.72) (0.06) | 0.24 (0.001) | 1.64 [0.90–2.97] (0.10) | 0.03 (0.92) | |
Outer Cysts location | 0.22 (0.04) | 0.13 (0.01–1.66) (0.11) | 0.32 (< 0.001) | 11.57 [0.63–209.50] (0.098) | 0.13 (0.29) | |
Outer fields location of DME Peak | 0.26 (0.012) | 7.09 [1.76–28.57] (0.006) | 0.28 (0.002) | 7.75 [1.65–35.71] (0.009) | 0.25 (0.18) | |
Main DME thickness | 0.2 (< 0.001) | 0.99 [0.98–1.021] (0.10) | 0.34 (< 0.001) | 1.01 [1.00–1.021] (0.052) | 0.01 (0.72) | |