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Table 4 Comparison of the evolution of main DME Extension, CMT and DME highest thickness between treated and non-treated eyes

From: Large-cube 30° × 25° optical coherence tomography in diabetic macular edema

  Treated eyes (94 eyes) Non-treated eyes (130)  
At baseline After treatment At baseline Follow-up visit
Extension of main DME outside ETDRS 54 37 36 51 P < 0.001*
CMT Above the normal values 52 24 13 20 P < 0.001*
Improvement of CMT   62   23 P < 0.001*
Improvement of Main DME thickness   75   45 P < 0.001*
  1. DME diabetic macular edema, ETDRS early treatment diabetic retinopathy study, CMT central macular thickness
  2. In bold italics: statistically significative (after Bonferroni adjustment in univariate analysis)
  3. *Fischer’s Exact Test
  4. CMT > 320 µm for male and > 305 µm for female
  5. Reduction of retinal thickness more than 10 µm