Skip to main content

Table 1 Characteristics of groups and comparison of mean thickness of each layer in eyes with and without iERM

From: Morphological alternation and influence of aqueous flare in idiopathic epiretinal membrane

  eyes with iERM control eyes without ERM P value* iERM stage 1 P value** iERM stage 2,3 P value***
n = 36 n = 109   n = 26   n = 10  
Age (years) 76.17 ± 6.16 77.81 ± 7.01 0.213a 76.38 ± 6.22 0.609b 75.60 ± 6.31 0.949b
Gender (male/female) 8/28 36/73 0.296d 4/22 0.182d 4/6 0.259d
Axial length (mm) 24.19 ± 1.23 23.73 ± 1.14  < 0.05a 24.17 ± 1.22 0.204b 24.26 ± 1.34 0.980b
Aqueous flare (pc/ms) 8.09 ± 3.97 7.17 ± 2.94 0.207a 8.06 ± 4.37 0.841b 8.16 ± 2.87 0.839b
Maximum length of retinal folds (µm)     26.92 ± 19.05   50.60 ± 26.58  < 0.01a
Total retinal thickness (µm)
Mean ± SD
 Zone 1 291.75 ± 49.48 232.63 ± 23.75  < 0.0001a 269.65 ± 35.91  < 0.0001c 349.20 ± 29.39  < 0.001c
 Zone 2 315.55 ± 23.22 287.03 ± 17.28  < 0.0001a 307.40 ± 17.97  < 0.0001b 336.76 ± 22.54  < 0.0001b
 Zone 3 281.87 ± 16.09 262.99 ± 14.48  < 0.0001a 278.46 ± 14.27  < 0.0001b 290.76 ± 17.83 0.0661b
Inner retinal thickness (µm)
Mean ± SD
 Zone 1 71.53 ± 22.19 49.44 ± 12.51  < 0.0001a 62.58 ± 15.54  < 0.001c 94.80 ± 20.27  < 0.001c
 Zone 2 119.47 ± 18.18 100.17 ± 11.46  < 0.0001a 114.63 ± 15.96  < 0.0001c 136.73 ± 18.27  < 0.05c
 Zone 3 112.30 ± 12.68 99.75 ± 11.12  < 0.0001a 110.10 ± 11.61  < 0.001b 117.99 ± 14.19 0.156b
Outer retinal thickness (µm)
Mean ± SD
 Zone 1 220.22 ± 31.35 183.19 ± 16.88  < 0.0001a 207.08 ± 25.82  < 0.0001c 254.40 ± 13.22  < 0.001c
 Zone 2 196.08 ± 15.81 186.87 ± 11.45  < 0.01a 192.77 ± 16.94  < 0.05c 204.69 ± 7.83  < 0.05c
 Zone 3 169.58 ± 8.93 163.24 ± 10.24  < 0.01a 168.35 ± 9.15 0.0512b 172.77 ± 7.87 0.458b
% Inner retinal thickness (%)
Mean ± SD
 Zone 1 24.12 ± 4.14 21.08 ± 4.08  < 0.001a 23.05 ± 3.75 0.0656b 26.90 ± 3.98  < 0.05b
 Zone 2 37.77 ± 4.21 34.84 ± 2.84  < 0.001a 37.26 ± 4.54  < 0.001c 39.07 ± 3.02 0.169c
 Zone 3 39.76 ± 2.79 37.76 ± 2.79  < 0.01a 39.49 ± 2.81  < 0.05b 40.48 ± 2.76 0.653b
% Outer retinal thickness (%)
Mean ± SD
 Zone 1 75.88 ± 4.14 78.92 ± 4.08  < 0.001a 76.94 ± 3.75 0.0656 73.10 ± 3.98  < 0.05b
 Zone 2 62.23 ± 4.21 65.16 ± 2.84  < 0.001a 62.74 ± 4.54  < 0.001c 60.93 ± 3.02 0.169c
 Zone 3 60.23 ± 2.79 62.12 ± 3.10  < 0.01a 60.51 ± 2.81  < 0.05b 59.52 ± 2.76 0.653b
Choroidal thickness (µm)
Mean ± SD
 Zone 1 210.39 ± 78.52 212.74 ± 57.58 0.869a 202.88 ± 58.79 0.611c 229.90 ± 117.43 0.983c
 Zone 2 204.98 ± 73.19 208.25 ± 57.04 0.782a 198.59 ± 56.29 0.613c 221.61 ± 107.74 0.976c
 Zone 3 193.86 ± 64.59 197.68 ± 52.49 0.722a 187.63 ± 50.51 0.627c 210.05 ± 92.90 0.999c
  1. Bold P values denote statistical signigficance. iERM, idiopatic epiretinal membrane
  2. *Between eyes with iERM and control eyes
  3. **Between control eyes and eye with iERM in stage1
  4. ***Between eyes with iERM stage 1 and eyes with iERM in stage 2 and 3
  5. aUnpaired t-test
  6. bUnpaired t-test with Tukey post-test
  7. cMann-Whitney test with Steel–Dwass post-test
  8. dFisher-test