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Table 1 Characteristics of groups and comparison of mean thickness of each layer in eyes with and without iERM

From: Morphological alternation and influence of aqueous flare in idiopathic epiretinal membrane

 

eyes with iERM

control eyes without ERM

P value*

iERM stage 1

P value**

iERM stage 2,3

P value***

n = 36

n = 109

 

n = 26

 

n = 10

 

Age (years)

76.17 ± 6.16

77.81 ± 7.01

0.213a

76.38 ± 6.22

0.609b

75.60 ± 6.31

0.949b

Gender (male/female)

8/28

36/73

0.296d

4/22

0.182d

4/6

0.259d

Axial length (mm)

24.19 ± 1.23

23.73 ± 1.14

 < 0.05a

24.17 ± 1.22

0.204b

24.26 ± 1.34

0.980b

Aqueous flare (pc/ms)

8.09 ± 3.97

7.17 ± 2.94

0.207a

8.06 ± 4.37

0.841b

8.16 ± 2.87

0.839b

Maximum length of retinal folds (µm)

   

26.92 ± 19.05

 

50.60 ± 26.58

 < 0.01a

Total retinal thickness (µm)

Mean ± SD

 Zone 1

291.75 ± 49.48

232.63 ± 23.75

 < 0.0001a

269.65 ± 35.91

 < 0.0001c

349.20 ± 29.39

 < 0.001c

 Zone 2

315.55 ± 23.22

287.03 ± 17.28

 < 0.0001a

307.40 ± 17.97

 < 0.0001b

336.76 ± 22.54

 < 0.0001b

 Zone 3

281.87 ± 16.09

262.99 ± 14.48

 < 0.0001a

278.46 ± 14.27

 < 0.0001b

290.76 ± 17.83

0.0661b

Inner retinal thickness (µm)

Mean ± SD

 Zone 1

71.53 ± 22.19

49.44 ± 12.51

 < 0.0001a

62.58 ± 15.54

 < 0.001c

94.80 ± 20.27

 < 0.001c

 Zone 2

119.47 ± 18.18

100.17 ± 11.46

 < 0.0001a

114.63 ± 15.96

 < 0.0001c

136.73 ± 18.27

 < 0.05c

 Zone 3

112.30 ± 12.68

99.75 ± 11.12

 < 0.0001a

110.10 ± 11.61

 < 0.001b

117.99 ± 14.19

0.156b

Outer retinal thickness (µm)

Mean ± SD

 Zone 1

220.22 ± 31.35

183.19 ± 16.88

 < 0.0001a

207.08 ± 25.82

 < 0.0001c

254.40 ± 13.22

 < 0.001c

 Zone 2

196.08 ± 15.81

186.87 ± 11.45

 < 0.01a

192.77 ± 16.94

 < 0.05c

204.69 ± 7.83

 < 0.05c

 Zone 3

169.58 ± 8.93

163.24 ± 10.24

 < 0.01a

168.35 ± 9.15

0.0512b

172.77 ± 7.87

0.458b

% Inner retinal thickness (%)

Mean ± SD

 Zone 1

24.12 ± 4.14

21.08 ± 4.08

 < 0.001a

23.05 ± 3.75

0.0656b

26.90 ± 3.98

 < 0.05b

 Zone 2

37.77 ± 4.21

34.84 ± 2.84

 < 0.001a

37.26 ± 4.54

 < 0.001c

39.07 ± 3.02

0.169c

 Zone 3

39.76 ± 2.79

37.76 ± 2.79

 < 0.01a

39.49 ± 2.81

 < 0.05b

40.48 ± 2.76

0.653b

% Outer retinal thickness (%)

Mean ± SD

 Zone 1

75.88 ± 4.14

78.92 ± 4.08

 < 0.001a

76.94 ± 3.75

0.0656

73.10 ± 3.98

 < 0.05b

 Zone 2

62.23 ± 4.21

65.16 ± 2.84

 < 0.001a

62.74 ± 4.54

 < 0.001c

60.93 ± 3.02

0.169c

 Zone 3

60.23 ± 2.79

62.12 ± 3.10

 < 0.01a

60.51 ± 2.81

 < 0.05b

59.52 ± 2.76

0.653b

Choroidal thickness (µm)

Mean ± SD

 Zone 1

210.39 ± 78.52

212.74 ± 57.58

0.869a

202.88 ± 58.79

0.611c

229.90 ± 117.43

0.983c

 Zone 2

204.98 ± 73.19

208.25 ± 57.04

0.782a

198.59 ± 56.29

0.613c

221.61 ± 107.74

0.976c

 Zone 3

193.86 ± 64.59

197.68 ± 52.49

0.722a

187.63 ± 50.51

0.627c

210.05 ± 92.90

0.999c

  1. Bold P values denote statistical signigficance. iERM, idiopatic epiretinal membrane
  2. *Between eyes with iERM and control eyes
  3. **Between control eyes and eye with iERM in stage1
  4. ***Between eyes with iERM stage 1 and eyes with iERM in stage 2 and 3
  5. aUnpaired t-test
  6. bUnpaired t-test with Tukey post-test
  7. cMann-Whitney test with Steel–Dwass post-test
  8. dFisher-test