Fig. 2

Probability of severe visual loss as a function of the CFT and the integrity or disruption of EPIS and IZ outer retinal layers. The logistic regression model predicts increased risk and a higher probability of severe visual impairment (3.74 OR with CI 95% = 2.07–6.77) (P = 0.001) when there is EPIS disruption (a), and a low risk of severe visual loss when this retinal layer is preserved (b). In the same manner, the logistic regression model predicts an increased risk (3.26 OR with CI 95% = 1.85–5.74) (P = 0.001) of visual impairment if IZ gets disrupted (c), and a low risk of severe visual loss when this retinal layer is preserved (d). EPIS ellipsoid portion of inner segments, IZ interdigitating zone