Table 1 Clinical and OCT features of patients with internal limiting membrane detachment (ILMD) following acute central retinal artery occlusion (CRAO)
No | Age/sex | Systemic disease | Affected eye | Duration of symptoms | IOP | VA at presentation | Fundus features | Clinical diagnosis | OCT features at the time of ILMD development | Time interval between presentation and ILMD | Ocular treatment given | Vision at final visit | OCT features at final visit | Follow-up duration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 35/M | None | LE | 1 Day | 13 | PL–ve | 1) Retinal whitening 2) Cherry red spot 3) An island of normal retina temporal to the optic disc 4) Normal optic nerve head | CRAO with CLA sparing | 1) Posterior vitreous opacities 2) Inner retinal thickening 3) Inner retinal opacification 4) Loss of retinal layer stratification 5) ILMD noted at the posterior pole with a few low intensity hyperreflective dots noted within the ILM detachment | 5 days | 1) Ocular massage 2) Anterior chamber paracentesis 3) Oral Acetazolamide 250 mg | PL–ve | Atrophy and thinning of the inner retinal layers with reattachment of ILMD | 28 |
2 | 30/M | CVA | RE | 7 days | 12 | PL–ve | 1) Pale optic nerve head 2) Peripapillary whitening 3) Retinal vessel attenuation 4) A thin atrophic retina 5) Possible macular hole | CRAO with macular hole | 1) Posterior vitreous opacities 2) Inner retinal thinning 3) ILMD noted at the posterior pole with a few hyperreflective dots noted within the ILMD 4) Full thickness macular hole defect | At presentation | 1) Oral Acetazolamide 250 mg | – | – | – |
3 | 69/F | None | LE | 7 days | 11 | CF 1mt | 1) Retinal opacification at the posterior pole 2) Cherry red spot 3) Retinal vessel attenuation | CRAO | 1) Posterior vitreous opacities 2) Normal retinal thickness 3) Retinal opacification 4) Normal foveal contour 5) ILMD at the fovea | At presentation | Referred to internist | – | – | – |
4 | 25/M | None | RE | 3 h | 16 | PL + ve | 1) Retinal whitening 2) Cherry red spot 3) Normal optic nerve head | CRAO | 1) Posterior vitreous opacities 2) Inner retinal thickening 3) Inner retinal opacification 4) Loss of retinal layer stratification 5) ILMD noted at the posterior pole with a few low intensity hyperreflective dots noted within the ILMD | 1 day | 1) Ocular massage 2) Anterior chamber paracentesis 3) Oral Acetazolamide 250 mg | PL + ve | Atrophy, thinning and necrosis of the retinal layers ILMD +  +  Macula hole +  +  | 14 |
5 | 15/M | None | RE | 1 days | 14 | PL + ve | 1) Retinal whitening 2) Cherry red spot | CRAO | 1) Posterior vitreous opacities 2) Inner retinal thickening 3) Inner retinal opacification 4) Loss of retinal layer stratification 5) ILMD noted at the posterior pole with a few low intensity hyperreflective dots and material noted within the ILMD | 3 days | 1) Ocular massage 2) Anterior chamber paracentesis 3) Oral Acetazolamide 250 mg | PL–ve | Atrophy and thinning of the inner retinal layers with reattachment of ILMD | 28 |