Table 1 Currently available anti-VEGF therapies
From: Pipeline therapies for neovascular age related macular degeneration
Generic | Brand name, manufacturer | Target/mechanism |
|---|---|---|
Pegaptanib sodium | Macugen; Bausch and Lomb, Rochester, New York | 165 isoform of VEGF-A |
Bevacizumab | Avastin; Genentech, San Francisco, California | All isoforms of VEGF-A |
Ranibizumab | Lucentis; Genentech, South San Francisco, California | All isoforms of VEGF-A |
Aflibercept | Eylea; Regeneron, Tarrytown, New York | VEGF-A and B, placental growth factor (PGF) |
Brolucizumab | Beovu; Novartis, Logo, Basel | VEGF-A |