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Table 2 Comparison of regression and recurrence rate between patients with retinopathy of prematurity received intravitreal Bevacizumab (IVB) and intravitreal Aflibercept (IVA)

From: Comparison of aflibercept and bevacizumab in the treatment of type 1 retinopathy of prematurity

Parameter

Level

Total

Type of treatment

p‡

IVB

IVA

Regression

Number (%)

854 (96.1%)

830 (96.0%)

24 (100.0%)

0.023

Estimated Median (days) (95% CI)†

 

10.0 (9.2 to 10.8)

14.0 (9.2 to 18.8)

 

Mean observed time (days) ± SD ¥

 

14 ± 10

22 ± 15

 

Median observed time (days) (range) ¥

 

10 (1 to 64)

16 (6 to 57)

 

Recurrence

Number (%)

47 (5.5%)

34 (3.9%)

14 (58.3%)

 < 0.001

Estimated Median (days) (95% CI)†

 

NA

96.0 (76.3 to 115.7)

 

Mean observed time (days) ± SD ¥

 

47

104

 

Median observed time (days) ¥

 

23

92

 
  1. Based on log-rank test
  2. Estimated time to have 50% of participants in the group to have the outcomes
  3. ¥ Computed in the occurred participants