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Table 2 Univariate analysis compared BCVA and findings of uncertain significance

From: Findings of uncertain significance by optical coherence tomography (OCT) as prognostic factors in neovascular age-related macular degeneration (nAMD) treated with ranibizumab

 

Eyes per group

Mean basal BCVA in ETDRS letters

Mean BCVA after loading dose in ETDRS letters

Difference in ETDRS letters

p value*

Without onion sign

51

33.1

35.6

 + 2.5

0.16

With onion sign

32

24.4

30

 + 5.6

0.04

Without prechoroidal cleft

65

32.9

36.6

 + 3.7

0.04

With prechoroidal cleft

18

18.3

21.9

 + 3.6

0.15

Without intraretinal pseudocyst

51

30.4

35.2

 + 4.8

0.002

With intraretinal pseudocyst

32

28.8

30.6

 + 1.8

0.54

Without subretinal pseudocyst

67

31.6

36.2

 + 4.6

0.005

With subretinal pseudocyst

16

21.9

21.9

0

1.0

Without choroidal caverns

66

31.3

35.7

 + 4.4

0.0065

With choroidal caverns

17

23.8

24.7

 + 0.9

0.83

  1. *Paired t Student