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Table 4 Benefits, risks and recommendations for assessment procedures done prior to administering intravitreal injection treatment

From: Are intravitreal injections essential during the COVID-19 pandemic? Global preferred practice patterns and practical recommendations

Procedure

Benefits

Risks during COVID-19 pandemic

Risk of deferring procedure

Situations where the procedure is indicated

Situations where the procedure can be deferred

Modifications to the procedure during COVID-19 pandemic

VA testing

Widely accepted functional visual assessment

Can be used to determine T&E decisions

Increasing contact time with patient and staff

Patients may not report vision loss

Visual outcomes less closely monitored

Treatment naïve patients

Patients who complain of visual loss

Patients receiving loading doses

Long-term patients with stable disease

Take VA starting from smallest letter and work upwards to save time

Pinhole vision may not be necessary

IOP measurement

Monitor glaucoma risk in IVT patients

Increased contact time with patient and staff

Aerosolized droplets from non-contact/pneumatic tonometry

Undetected IOP rise

High risk glaucoma patients

Cupped disc

Post intravitreal steroid injection for the first time

Routine follow up

No history of glaucoma or disc cupping

Already has separate glaucoma follow-up appointment

Suspend the use of non-contact tonometry, use Goldmann applanation or I-care tonometry

Pupil dilation

Allows the examination of the peripheral retina

Increased contact time with patient and staff; spread of COVID-19 from contaminated eye drops

Risk of missing retinal pathology

Treatment naive

High myopia

Extra-foveal disease

Visual field loss

Long-term patients with stable disease

Dilation eye drops should be administered only once on arrival, if needed patient can be given disposable minims of eye drops for repeated administration

OCT

Objective structural assessment of active disease

Can be used to determine T&E decisions

Increased contact time with staff

Undetected Worsening disease activity

Early recurrence with no VA loss not detected

Missed screening of fellow eye

Treatment naïve

4 weeks after 3rd loading dose

Patients receiving loading doses

Long-term patients with stable disease

Known maximum treatment interval

Plastic shield in machines where patient faces the technician

Keep scanning protocol to a minimum

Decentralise imaging service

Slit-lamp examination

Detection on non-retinal pathology

Assessment of the retinal periphery

Detection of new areas of bleeding

Increased close contact with staff

Undetected Non-retinal pathology and peripheral retinal pathology

Undetected new retinal hemorrhages or rubeosis

Treatment naïve cases

Patients with worsening visual acuity

Patients receiving loading doses

Long-term patients with stable disease

Plastic shield in machines where patient faces the doctor

N95 masks and goggles for high risk patients

Ophthalmology consultation

Direct reporting of symptoms

Patient doctor rapport

Increased prolonged close contact with doctor

Undetected pathology not picked up by imaging

Treatment naïve cases

Patients receiving loading doses

Long-term patients with stable disease

To be replaced by telephone or video consultation

  1. VA: visual acuity, IOP: intra-ocular pressure, OCT: optical coherence tomography, loading doses refer to intravitreal anti-VEGF therapy