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Table 5 Correlation between plasma level of lipid components and VEGF with their levels in vitreous among HC and T2DM (subjects from DNR + MNPDR + HRPDR) group

From: Do different lipid components accelerate the pathogenesis and severity of Diabetic Retinopathy?

Parameters

HC

T2DM

TL (mg/dl)

r = 0.35, p = 0.47

r = 0.76, p < 0.0001

FFA (mmol/L)

r = 0.21, p = 0.64

r = 0.67, p < 0.0001

MDA (µmol/L)

r = 0.31, p = 0.54

r = 0.84, p < 0.0001

HNE (pg/ml)

r = 0.32, p = 0.49

r = 0.79, p < 0.0001

HLY (nmol/L)

r = 0.29, p = 0.56

r = 0.73, p < 0.0001

VEGF (pg/L)

r = 0.28, p = 0.60

r = 0.72, p < 0.0001

  1. The DNR, MNPDR and HRPDR groups are combined together and termed as Type 2 Diabetes Mellitus (T2DM) group. Pearson or Spearman's rank correlation coefficient (r) was used and a value of p < 0.05 was considered as statistically significant
  2. TL, total lipid; FFA, free fatty acid; HNE, 4-Hydroxynonenal; MDA, malondialdehyde; HLY, hexanoyl-lysine; VEGF, vascular endothelial growth factor