Table 1 Inclusion and exclusion criteria for participation in the study

 Age more than 50 years

 Typical morphology of age-related macular degeneration (AMD)

 Lesion affecting the central subfield (1 mm around the centre)

 Active choroidal neovascularization comprising more than 50% of the total lesion area

 Intraretinal or Subretinal Fluid in central subfield

 Best-corrected visual acuity between 20/32 to 20/400

 Any fibrosis or geographical atrophy of central subfield

 Any intra or periocular infection or inflammation

 If the patient had received any approved treatment for neovascular AMD other than micronutrient supplementation

 Any concurrent intraocular disease like diabetic retinopathy

 History of drug sensitivity/ allergic reactions to research interventions

 Stroke or myocardial infarction in the 90 days preceding to baseline visit