Skip to main content

Table 2 Retreatment criteria for patients requiring additional respective injections (Brolucizumab or Aflibercept) at each visit

From: Efficacy and safety of brolucizumab versus aflibercept in patients with neovascular age-related macular degeneration: a randomized trial in Indian patients

Retreatment criteria

 BCVA decrease by 0.10 from BCVA gained at 12-week review or last visit

 OCT CMT increase by 75 µm from CMT attained at 12-week review

 The appearance of new IRF spaces in central 1.5 mm, i.e. 750 µm from the foveal centre

 The appearance of new SRF space in central 1.5 mm, i.e. 750 µm from the foveal centre

 Increase in SRF height from the status achieved at 12-week review

  1. BCVA Best-corrected visual acuity, OCT Optical coherence tomography, CMT Central macular thickness, IRF intraretinal fluid, SRF subretinal fluid