Characteristic | Whole cohort | SCR | PSCR | ||||
---|---|---|---|---|---|---|---|
n = 1904 | Yes (n = 953) n (%) | No (n = 951) n (%) | P-valuea | Yes (n = 423) n (%) | No (n = 1481) n (%) | P-valuea | |
Age at entry | Â | Â | Â | Â | Â | Â | Â |
 Median (years)b | 17.0 (10.0–26.0) | 22.0 (14.0–29.0) | 13.0 (7.0–21.0) |  < 0.001 | 25.5 (18.0–32.0) | 15.0 (8.0–23.0) |  < 0.001 |
 Adult | 852 (44.7%) | 567 (59.5%) | 285 (30.0%) |  < 0.001 | 315 (74.5%) | 537 (36.3%) |  < 0.001 |
 Pediatric | 1052 (55.3%) | 386 (40.5%) | 666 (70.0%) |  | 108 (25.5%) | 944 (63.7%) |  |
Sex | Â | Â | Â | Â | Â | Â | Â |
 Female | 1051 (55.2%) | 493 (51.8%) | 558 (58.7%) | 0.003 | 213 (50.5%) | 838 (56.6%) | 0.025 |
 Male | 851 (44.7%) | 458 (48.2%) | 393 (41.3%) |  | 209 (49.5%) | 642 (43.4%) |  |
Race | Â | Â | Â | Â | Â | Â | Â |
 Black | 1864 (97.9%) | 937 (98.8%) | 927 (97.9%) | 0 .103 | 419 (99.8%) | 1445 (98.0%) | 0.101 |
 Other races | 31 (1.6%) | 11 (1.2%) | 20 (2.1%) |  | 1 (0.2%) | 30 (2.0%) |  |
Smoking | 588 (30.9%) | 400 (44.9%) | 188 (25.6%) |  < 0.001 | 216 (53.1%) | 372 (30.6%) |  < 0.001 |
Eye symptoms | 446 (23.4%) | 258 (27.1%) | 188 (19.8%) |  < 0.001 | 146 (34.5%) | 300 (20.3%) |  < 0.001 |
BP ≥ 130/90 (mmHg) | 152 (8.0%) | 101 (10.8%) | 51 (5.6%) |  < 0.001 | 55 (13.2%) | 97 (6.8%) |  < 0.001 |
BMI ≥ 25 (kg/m2) | 183 (9.6%) | 116 (12.7%) | 67 (7.4%) |  < 0.001 | 67 (16.5%) | 116 (8.2%) |  < 0.001 |
Genotype | Â | Â | Â | Â | Â | Â | Â |
 SCAc | 1403 (73.7%) | 682 (71.7%) | 719 (75.8%) | 0.041 | 253 (60.0%) | 1148 (77.7%) |  < 0.001 |
 Variantd | 501 (26.3%) | 269 (28.3%) | 229 (24.2%) |  | 169 (40.0%) | 329 (22.3%) |  |