Fig. 1

Reflectance and retroillumination scanning laser ophthalmoscope (SLO) as well as optical coherence tomography (OCT) images of the right retina of a 75-year-old female with neovascular age-related macular degeneration, small subretinal hemorrhages, a large vascularized retinal pigment epithelial detachment and numerous drusen. A Reflectance multiwavelength SLO image. B Retroillumination SLO image taken with a deviated-to-the-right (DR) confocal aperture. C Retroillumination SLO image taken with a deviated-to-the-left (DL) aperture. D Retroillumination SLO image taken with a ring aperture (RA; annular aperture). Prominent lesion highlighting and border shading in B and C are absent with the Mirante ring aperture but present in published images with annular apertures using other SLO retroillumination systems. [1,2,3,4, 49, 54] E Segmented retinal pigment epithelium three-dimensional OCT topography differing from retroillumination shading patterns in B and C (inset shows B-scan along white arrow). F En face structural OCT image corresponding roughly to tissue planes of RPE topography in E and drusen in B and C