Fig. 1

Visual acuity outcomes (FAS). a, Mean change in BCVA letter score over 12 months in treatment-naïve and previously treated patients; b, Mean change in BCVA letter score at months 6 and 12 in treatment-naïve and previously treated patients by number of injections received in the first 3 months of treatment; c, Mean change in BCVA letter score at months 6 and 12 in treatment-naïve and previously treated patients by overall number of injections; d, Mean absolute BCVA letter score at months 6 and 12 in treatment-naïve and previously treated patients; e, Proportion of treatment-naïve and previously treated patients by BCVA categorical score change at month 12. Missing data were imputed using LOCF. Data in a were collected monthly ± 15 days. In b–d, data for the 6-month time point were collected at 6 months ± 30 days; data for the 12-month time point were collected at 12 months ± 60 days. Error bars denote standard error. BCVA best-corrected visual acuity, FAS full analysis set, LOCF last observation carried forward