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Fig. 1 | International Journal of Retina and Vitreous

Fig. 1

From: A customized regimen of intravitreal aflibercept for the treatment of choroidal neovascularization secondary to different chorioretinal diseases

Fig. 1

A Top left. Color fundus photo of the left eye of a 19-year-old male following laser pointer injury to the macular area. The macular area shows a well-circumscribed area of neurosensory detachment approximately 2-disc diameter in size (arrows) with central SMH and hard exudates. Top right. SS-OCT of the same eye in a line scan mode shows a sub-foveal amorphous hyperreflective lesion above the RPE. Note the overlying hyporeflective cystic space formation and multiple hyperreflective foci. Bottom. SS-OCTA image in a 3 × 3 mm field of the outer retina and the corresponding flow density map. Note the hyperintense signal with dense arborization, vascular anastomosis, and looping that are characteristic of an active neovascular network. Note the high flow within the neovascular network in the flow density image. B Top left. Color fundus photo of the same eye 6 months after a single IVA injection. The macular area shows resolution of neurosensory detachment, and SMH, which are replaced by a well-circumscribed submacular yellowish elevated lesion consistent with scar formation. Top right. SS-OCT in a line scan mode shows a parafoveal dome-shaped hyperreflective lesion above the RPE with the resolution of the previously noted cystic spaces. Bottom. SS-OCTA image in a 3 × 3 mm field of the outer retina and the corresponding flow density map. Note the resolution of the previously noted hyperintense signal of the neovascular network and the disappearance of high flow in the flow density map

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